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  • Total synthesis of 10-norparvulenone and of O-methylasparvenone using a xanthate-mediated free radical addition-cyclization sequence.

Total synthesis of 10-norparvulenone and of O-methylasparvenone using a xanthate-mediated free radical addition-cyclization sequence.

Organic letters (2003-09-26)
Alejandro Cordero Vargas, Béatrice Quiclet-Sire, Samir Z Zard
ABSTRACT

[reaction: see text] A short synthesis of (+/-)-10-norparvulenone and (+/-)-O-methylasparvenone was developed starting from commercially available m-methoxyphenol, hinging on a xanthate-mediated addition-cyclization sequence for the construction of the alpha-tetralone subunit.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
3-Methoxyphenol, 96%