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  • [Effect of dietary intoxication by mercury salts on cysteine proteinase activity in rat tissues].

[Effect of dietary intoxication by mercury salts on cysteine proteinase activity in rat tissues].

Izvestiia Akademii nauk. Seriia biologicheskaia (2003-03-22)
L A Bondareva, N N Nemova, E I Kiaĭviariaĭnen, M Iu Krupnova, V V Ostashkova
ABSTRACT

The experiments on dietary intoxication of rats by HgI2 or Hg(NO3)2 show that the activities of lysosomal proteinase cathepsin B and cytosolic Ca(2+)-activated proteinases (calpains I and II) in the liver and kidney depend on the mercury salt solubility and the exposure duration. Mercury iodide and nitrate contribute more to inhibiting cathepsin B and calpains activities in the above tissues, respectively.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Mercury(II) iodide, ACS reagent, ≥99.0%
Sigma-Aldrich
Mercury(II) iodide red, puriss. p.a., ACS reagent, red, ≥99.0% (RT)