- Synthesis of taurine analogues from alkenes: preparation of 2-aminocycloalkanesulfonic acids.
Synthesis of taurine analogues from alkenes: preparation of 2-aminocycloalkanesulfonic acids.
Advances in experimental medicine and biology (2002-01-15)
F Machetti, M Cacciarini, F Catrambone, F M Cordero, M Frosini, F De Sarlo
PMID11787625
ABSTRACT
(+/-)trans 2-Aminocyclohexanesulfonic acid and (+/-)trans 2-aminocyclopentanesulfonic acid were prepared from cyclohexene and cyclopentene respectively by sulfur monochloride addition, followed by oxidation to 2-chlorosulfonic acid and substitution of chlorine.