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  • Protoboration of Alkynes and Miyaura Borylation Catalyzed by Low Loadings of Palladium.

Protoboration of Alkynes and Miyaura Borylation Catalyzed by Low Loadings of Palladium.

The Journal of organic chemistry (2022-10-13)
Lei Xu, Zheng Dong, Qi Zhang, Ning Deng, Shi-Yu Li, Hua-Jian Xu
ABSTRACT

The versions of Miyaura borylation and protoboration of alkynes catalyzed by low loadings of palladium (400 mol ppm = 0.04 mol %) have been developed. These transformations have a broad substrate scope, good functional-group compatibility, and gram-scale synthetic ability.

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tBuXPhos ChemBeads