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  • Multiple synchronous primary malignant neoplasms: A case report and literature review.

Multiple synchronous primary malignant neoplasms: A case report and literature review.

Oncology letters (2023-09-04)
Linlin Hao, Lihui Zhang, Chuanjie Xu, Min Jiang, Geyi Zhu, Jie Guo
ABSTRACT

Multiple primary malignant neoplasms (MPMN) are defined as two or more primary malignancies diagnosed in an individual. There is no association between these cancers, which can be classified into synchronous and heterochronous cancers depending on the time of diagnosis. The present study presented a rare case of bilateral breast, endometrial, cervical and ovarian cancers. Through thorough physical examination, pathology and immunohistochemistry, it could be determined that bilateral breast, endometrial and cervical cancers were primary malignant tumors and that ovarian cancer cannot be excluded as a result of metastasis. the present study also summarized the definitions, risk factors, prevalence characteristics, diagnostic ideas and treatment options for MPMN by reviewing the literature.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Anti-Cytokeratin AE1/AE3 Antibody, recognizes acidic & basic cytokeratins, clone AE1/AE3, clone AE1/AE3, Chemicon®, from mouse
Sigma-Aldrich
Anti-CGA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution