- Repulsive factors and axon regeneration in the CNS.
Repulsive factors and axon regeneration in the CNS.
Current opinion in neurobiology (2001-02-17)
A E Fournier, S M Strittmatter
PMID11179877
ABSTRACT
During the past year, a major advance in the study of axon regeneration was the molecular cloning of Nogo. The expression of Nogo protein by CNS myelin may be a major factor in the failure of CNS axon regeneration. The effect of disrupting Nogo-dependent axon inhibition can now be studied conclusively. In related work, immunization with a Nogo-containing CNS myelin preparation was shown to promote regeneration and dramatic functional recovery after spinal cord trauma.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Neurite Outgrowth Assay Kit (3 µm), The NS220 Neurite Outgrowth Assay Kit (3 µm) is based on the use of Millicell cell culture inserts (chambers) containing a permeable membrane with 3-μm pores at the base.
Sigma-Aldrich
Neurite Outgrowth Assay Kit (1 µm), The NS225 Neurite Outgrowth Assay Kit (1 μm) is based on the use of Millicell cell culture inserts (chambers) containing a permeable membrane with 1 μm pores at the base.