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Merck
CN

S1876

D-Sorbitol

≥98% (GC)

Synonym(s):

D-Glucitol

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About This Item

Empirical Formula (Hill Notation):
C6H14O6
CAS Number:
Molecular Weight:
182.17
UNSPSC Code:
12352201
NACRES:
NA.21
PubChem Substance ID:
EC Number:
200-061-5
Beilstein/REAXYS Number:
1721899
MDL number:
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vapor density

<1 (vs air)

Quality Level

vapor pressure

<0.1 mmHg ( 25 °C)

assay

≥98% (GC)

form

powder or crystals

color

white

useful pH range

5.0-7.0 (25 °C, 182 g/L)

mp

98-100 °C (lit.)

solubility

water: 200 mg/mL, clear, colorless

SMILES string

OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO

InChI

1S/C6H14O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3-12H,1-2H2/t3-,4+,5-,6-/m1/s1

InChI key

FBPFZTCFMRRESA-JGWLITMVSA-N

Application

May be used for washing spheroplasts and in isoelectric focusing to minimize endoosmotic flow in agarose gels. May be used to induce osmotic stress.

Biochem/physiol Actions

D-Sorbitol is a sugar alcohol that is commonly used as a sugar substitute. It occurs naturally and is also produced synthetically from glucose. The food industry uses D-sorbitol as an additive in the form of a sweetener, humectant, emulsifier, thickener, or dietary supplement. D-Sorbitol has also been found in cosmetics, paper, and pharmaceuticals. Naturally, D-sorbitol occurs widely in plants via photosynthesis, ranging from algae to higher order fruits of the family Rosaceae.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.


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Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Articles

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Explore how carbohydrates function as excipients and carriers in drug delivery, with insights into mechanisms, case studies, and future trends.


Youngkook Kwon et al.
ChemSusChem, 6(3), 455-462 (2013-01-25)
This Full Paper addresses the electrocatalytic hydrogenation of glucose to sorbitol or 2-deoxysorbitol on solid metal electrodes in neutral media. Combining voltammetry and online product analysis with high-performance liquid chromatography (HPLC), provides both qualitative and quantitative information regarding the reaction
J M van Griensven et al.
Clinical pharmacology and therapeutics, 58(6), 631-640 (1995-12-01)
To examine the effect of diabetes mellitus on the pharmacokinetics of tolrestat and to investigate its effect on red blood cell sorbitol levels according to a new pharmacodynamic model for this class of drugs. Single and multiple doses of tolrestat
Beau Op de Beeck et al.
ChemSusChem, 6(1), 199-208 (2013-01-12)
The catalytic valorization of cellulose is currently subject of intense research. Isosorbide is among the most interesting products that can be formed from cellulose as it is a potential platform molecule and can be used for the synthesis of a



Global Trade Item Number

SKUGTIN
S1876-100G04061835549191
S1876-500G04061835549238
S1876-10MG04061835549214
S1876-10KG04061835549207
S1876-5KG04061835549245
S1876-1KG04061835549221