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Merck
CN

T5535

Thiabendazole

powder, suitable for plant cell culture, BioReagent

Synonym(s):

2-(4-Thiazolyl)benzimidazole

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About This Item

Empirical Formula (Hill Notation):
C10H7N3S
CAS Number:
148-79-8
Molecular Weight:
201.25
NACRES:
NA.72
PubChem Substance ID:
24900297
UNSPSC Code:
10171502
EC Number:
205-725-8
MDL number:
MFCD00005587
Beilstein/REAXYS Number:
611403

Key Documents

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Product Name

Thiabendazole, BioReagent, suitable for plant cell culture, powder

InChI key

WJCNZQLZVWNLKY-UHFFFAOYSA-N

InChI

1S/C10H7N3S/c1-2-4-8-7(3-1)12-10(13-8)9-5-14-6-11-9/h1-6H,(H,12,13)

SMILES string

c1ccc2[nH]c(nc2c1)-c3cscn3

product line

BioReagent

form

powder

technique(s)

cell culture | plant: suitable

color

light yellow

antibiotic activity spectrum

fungi

application(s)

agriculture

mode of action

enzyme | inhibits

Quality Level

200

Gene Information

human ... CYP2C9(1559)

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Application

Thiabendazole, a metal chelator and helminth-specific fumarate reductase inhibitor, is used primarily as an anthelmintic to control infections by helminth organisms. It is also used to control mold and fungal growth in plants.

General description

Chemical structure: imidazole

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place.Storage class (TRGS 510): Non Combustible Solids

pictograms

Environment
GHS09

signalword

Warning

hcodes

H410

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves

Regulatory Information

农药列管产品
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Certificates of Analysis (COA)

Lot/Batch Number
0000457380
0000457380
0000436533
0000436533
SLCM8850

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Alfredo Santovito et al.
Archives of toxicology, 85(6), 689-693 (2010-10-13)
Thiabendazole is a benzimidazole-derived compound widely employed in agriculture as anthelmintic and fungicide. It is also used as a post-harvest fungicide for imported citrus fruits during transport and storage, and thus, it was found at high concentration in fruits and
Petr Heneberg et al.
Scientific reports, 10(1), 7077-7077 (2020-04-29)
Neonicotinoid insecticides are associated with a decline in the diversity and distribution of bees and wasps (Hymenoptera: Aculeata). The effects of neonicotinoids on the metamorphosis of aculeates have never been addressed in detail; however, recent evidence suggests that neonicotinoids induce
Stuart Dashper et al.
Antimicrobial agents and chemotherapy, 54(3), 1311-1314 (2009-12-30)
Porphyromonas gingivalis is a major pathogen of chronic periodontitis and exists in a biofilm on the surface of the tooth root. Oxantel, a cholinergic anthelmintic and fumarate reductase inhibitor, significantly inhibited biofilm formation by P. gingivalis and disrupted established biofilms
Zeno Bisoffi et al.
PLoS neglected tropical diseases, 5(7), e1254-e1254 (2011-08-05)
Strongyloidiasis may cause a life-threatening disease in immunosuppressed patients. This can only be prevented by effective cure of chronic infections. Direct parasitologic exams are not sensitive enough to prove cure if negative. We used an indirect immune fluorescent antibody test
Andrew C Kotze et al.
PLoS neglected tropical diseases, 5(6), e1203-e1203 (2011-07-09)
Current efforts to control human soil-transmitted helminths (STHs) involve the periodic mass administration of benzimidazole drugs to school aged children and other at- risk groups. Given that high levels of resistance to these drugs have developed in roundworms of livestock
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