SRP4145
IL-6 from rat
recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC)
Synonym(s):
MGI-2, B cell differentiation factor (BCDF), BSF-2, HPGF, HSF, IFN-b2
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About This Item
biological source
rat
recombinant
expressed in E. coli
assay
≥90% (HPLC), ≥90% (SDS-PAGE)
form
lyophilized
potency
<0.01 ng/mL ED50
mol wt
~21.7 kDa
packaging
pkg of 10 μg
impurities
endotoxin, tested
NCBI accession no.
shipped in
wet ice
storage temp.
−20°C
Gene Information
rat ... Il6(24498)
General description
Interleukin- 6 (IL-6) is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B cells and T cells. It is a pro-inflammatory cytokine. IL-6 originates from mononuclear phagocytes, T and B lymphocytes, vascular endothelial cells and fibroblasts. It has a role in various physiological and pathological processes. IL-6 plays an important role in intracellular signaling pathways. Recombinant rat IL-6 is a 21.7kDa protein containing 187 amino acid residues.
Physical form
Lyophilized without any additives.
Preparation Note
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
Reconstitute in 10 mM HCl to a concentration of 0.1-1.0 μg/μL. The solution can then be diluted into other aqueous buffers.
Regulatory Information
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Targeting interlukin-6 to relieve immunosuppression in tumor microenvironment.
Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine (2017)
Yongpan Huang et al.
BMC complementary medicine and therapies, 23(1), 2-2 (2023-01-04)
The necessity of increasing the efficiency of organ preservation has encouraged researchers to explore the mechanisms underlying diabetes-related myocardial injuries. This study intended to evaluate the protective effects of oxymatrine (OMT) in myocardial injury caused by type 2 diabetes mellitus.
Meta-analysis of the role of IL-6 rs1800795 polymorphism in the susceptibility to prostate cancer: Evidence based on 17 studies.
Liu TZ
Medicine (2017)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SRP4145-10UG | 04061837226212 |