P4691
Protein G-Agarose, Fast Flow from Streptococcus sp.
saline suspension
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About This Item
UNSPSC Code:
41106500
MDL number:
Form:
saline suspension
form
saline suspension
extent of labeling
≥2 mg per mL
matrix
Highly cross-linked 4% beaded agarose, fast flow
matrix activation
cyanogen bromide
matrix attachment
amino
matrix spacer
1 atom
capacity
≥20 mg/mL binding capacity (human IgG (I 4506))(in 20 mM sodium phosphate, pH 7.0)
storage temp.
2-8°C
Application
Protein G-agarose is used in affinity chromatography, protein chromatography, antibody purification and characterization, immunoaffinity matrices, protein A, G and L resins, and purification and detection. Protein G-agarose has been used to study breast cancer and falsely elevated thyroid-stimulating hormone (TSH).
Physical form
Suspension in 0.5 M NaCl containing 20% ethanol as a preservative
Preparation Note
Prepared with a genetically engineered Protein G which retains its high affinity for IgG and lacks albumin and Fab binding sites and membrane binding regions.
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Bin Yi et al.
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The Journal of pharmacology and experimental therapeutics, 324(1), 261-269 (2007-10-06)
Previously we have demonstrated that 3',4'-dihydroxyflavonol (DiOHF), a novel synthetic flavonol, protects against ischemia reperfusion injury in both heart and brain. In this study, we characterized the pharmacological effects of DiOHF on phagocytic and vascular NADPH oxidase. Superoxide release (lucigenin-enhanced
L Zahradova et al.
Neoplasma, 59(4), 440-449 (2012-04-12)
In a phase II clinical study, pretreated multiple myeloma patients with relapsing or stable disease received autologous anticancer vaccine containing dendritic cells loaded with Id-protein. Patients received a total of 6 vaccine doses intradermally in monthly intervals. No clinical responses were observed.