Recommended Products
biological source
microbial (Staphylococcus roseus)
Quality Level
Assay
≥98% (HPLC)
form
solid
color
white to off-white
solubility
DMSO: >5 mg/mL
H2O: insoluble
storage temp.
2-8°C
SMILES string
O=C1C=C(Oc2c1cccc2-c3ccccc3)N4CCOCC4
InChI
1S/C19H17NO3/c21-17-13-18(20-9-11-22-12-10-20)23-19-15(7-4-8-16(17)19)14-5-2-1-3-6-14/h1-8,13H,9-12H2
InChI key
CZQHHVNHHHRRDU-UHFFFAOYSA-N
Related Categories
General description
Application
- phosphoinositide 3-kinase (PI3K) in human lung cancer cell line
- autophagy in mesenchymal stem cells (MSCs).
- serine/threonine-specific protein kinase (AKT) signaling in fibroblasts and cardiac cells.
Biochem/physiol Actions
Features and Benefits
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What is the solution stability in DMSO for Product L9908, LY-294,002 hydrochloride?
After reconstitution in DMSO, aliquot and freeze the stock solution at -20 °C. DMSO stock solutions are stable for at least 1 month at -20 °C.
What is the recommended concentration for using Product L9908, LY-294,002 hydrochloride?
One can use this product at 50 uM concentration.
Can I use Product L9908, LY-294,002 hydrochloride, in conjugation with Wortmannin?
Sigma-Aldrich has not done any such testing, but the following references may be helpful: Phosphatidylinositol 3´-Kinase Is a Critical Mediator of Interferon-γ-Induced Increases in Enteric Epithelial Permeability E-selectin permits communication between PAF receptors and TRPC channels in human neutrophils Activation of Phosphoinositide 3´-kinase in Response to High Glucose Leads to Regulation of Reactive Oxygen Species Related Nuclear Factor-κB Activation and Cyclooxygenase-2 Expression in Mesangial Cells
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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