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Merck
CN

L7414

N-Lauroylsarcosine sodium salt solution

20%, Molecular Biology

Synonym(s):

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Linear Formula:
CH3(CH2)10CON(CH3)CH2COONa
CAS Number:
Molecular Weight:
293.38
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
5322974
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biological source

plant

Quality Level

grade

Molecular Biology

description

anionic

assay

19-21%

form

liquid

mol wt

293.38 g/mol

concentration

19-21% (Titration by HClO4), 20%

solubility

water: soluble at 20 °C

foreign activity

DNase, RNase, and protease, none detected

SMILES string

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

InChI key

KSAVQLQVUXSOCR-UHFFFAOYSA-M

General description

N-Lauroylsarcosine sodium salt solution is an anionic surfactant which can be used in DNA extraction.

Application

N-Lauroylsarcosine sodium salt has been used in a study to assess the mechanisms underlying surfactant-induced itching. It has also been used in a study to investigate the formation of pH-responsive, stable vesicles resulting from an interaction with N-cetylpyridinium chloride (CPC) and N-dodecylpyridinium chloride (DPC) in aqueous mixtures.

Features and Benefits

N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

512.6 °F

flash_point_c

267 °C



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Interaction of sodium N-lauroylsarcosinate with N-alkylpyridinium chloride surfactants: Spontaneous formation of pH-responsive, stable vesicles in aqueous mixtures
Ghosh, S. and J. Dey
Journal of Colloid and Interface Science, 358, 9-9 (2011)
Alejandro Álvarez-Quilón et al.
Nature communications, 11(1), 910-910 (2020-02-16)
The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established tumour suppressor whose loss is the cause of the neurodegenerative and cancer-prone syndrome Ataxia-Telangiectasia (A-T). A-T patients and Atm-/- mouse models
Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust



Global Trade Item Number

SKUGTIN
L7414-50ML04061838258397
L7414-10ML04061838174710