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About This Item
Empirical Formula (Hill Notation):
C17H21NO4 · HBr
CAS Number:
Molecular Weight:
384.26
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41116107
EC Number:
217-742-8
MDL number:
Product Name
Fenoterol hydrobromide,
InChI key
SGZRQMALQBXAIQ-UHFFFAOYSA-N
InChI
1S/C17H21NO4.BrH/c1-11(6-12-2-4-14(19)5-3-12)18-10-17(22)13-7-15(20)9-16(21)8-13;/h2-5,7-9,11,17-22H,6,10H2,1H3;1H
SMILES string
Br[H].CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2
originator
Boehringer Ingelheim
Quality Level
Gene Information
human ... ADRB2(154)
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Related Categories
Application
Fenoterol hydrobromide has been used in chromatography-tandem mass spectrometry (LC&-MS-MS) for specific and sensitive detection of β-agonists (BAG).
Biochem/physiol Actions
β2-adrenoceptor agonist; bronchodilator.
Features and Benefits
This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
General description
Fenoterol hydrobromide is a sympathomimetic drug. It is used to treat asthma, bronchitis and emphysema. Fenoterol administration might be linked to liver damage. It has anti-inflammatory effects on eosinophil function.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
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Julia J Rucklidge et al.
Human psychopharmacology, 27(5), 440-454 (2012-07-12)
To compare two micronutrient (vitamins and minerals) formulas (Berocca™ and CNE™) and assess their impact on emotions and stress related to the 6.3 earthquake on February 22(nd) 2011 in Christchurch, New Zealand. 91 adults experiencing heightened anxiety or stress 2-3 months
Lawrence Toll et al.
Molecular pharmacology, 81(6), 846-854 (2012-03-22)
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a molecule with a G protein-coupled
Inhibition by fenoterol of human eosinophil functions including beta2-adrenoceptor-independent actions
Tachibana A, et al.
Clinical and Experimental Immunology, 130(3), 415-423 (2002)
Joanne Chung Yan Yeung et al.
Analytica chimica acta, 742, 37-44 (2012-08-14)
In vivo solid-phase microextraction (SPME) can be used to sample the circulating blood of animals without the need to withdraw a representative blood sample. In this study, in vivo SPME in combination with liquid-chromatography tandem mass spectrometry (LC-MS/MS) was used
Krzysztof Jozwiak et al.
Chirality, 23 Suppl 1, E1-E6 (2011-05-28)
The β(2) adrenergic receptor (β(2)-AR) is a model system for studying the ligand recognition process in G protein-coupled receptors. Fenoterol (FEN) is a β(2)-AR selective agonist that has two centers of chirality and exists as four stereoisomers. Radioligand binding studies
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