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E4375

Sigma-Aldrich

(−)-Epinephrine (+)-bitartrate salt

solid

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Synonym(s):
L-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol D-hydrogen bitartrate salt, L-Adrenaline (+)-bitartrate salt, L-Adrenaline D-hydrogentartrate, L-Epinephrine D-hydrogentartrate
Empirical Formula (Hill Notation):
C9H13NO3 · C4H6O6
CAS Number:
51-42-3
Molecular Weight:
333.29
EC Number:
200-097-1
MDL number:
MFCD00035077
UNSPSC Code:
12352200
PubChem Substance ID:
24277774
NACRES:
NA.77

form

solid

Quality Level

200

color

white

solubility

H2O: soluble
alcohol: soluble

storage temp.

2-8°C

SMILES string

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3.C4H6O6/c1-10-5-9(13)6-2-3-7(11)8(12)4-6;5-1(3(7)8)2(6)4(9)10/h2-4,9-13H,5H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

InChI key

YLXIPWWIOISBDD-NDAAPVSOSA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)

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General description

Epinephrine is a hormone, which is also termed as adrenaline. It is a monoamine and catecholamine.

Application

(-)Epinephrine (+)-bitartrate salt has been used:
  • to test the possible existence of β-adrenergic vasodilation
  • to infuse into the adipose region to minimize blood loss and tissue contamination
  • as a platelet agonist in the preparation of optimal platelet aggregometry 96-well plates
  • in the measurement of total superoxide dismutase (tSOD) enzymatic activity

Biochem/physiol Actions

Epinephrine is mainly liberated from adrenal medulla in response to stress, that is facilitated through sympathetic fibers.
Adrenergic receptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors, β-Adrenoceptors and Dopamine, Norepinephrine and Epinephrine Synthesis pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Caution

Light sensitive

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H300

Hazard Classifications

Acute Tox. 1 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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