Skip to Content
Merck
CN
All Photos(1)

Documents

Safety Information

E4250

Sigma-Aldrich

(−)-Epinephrine

Sign Into View Organizational & Contract Pricing
All Photos(1)
Synonym(s):
(−)-Adrenalin, (R)-(−)-3,4-Dihydroxy-α-(methylaminomethyl)benzyl alcohol, L-Adrenaline, L-Epinephrine
Linear Formula:
(HO)2C6H3CH(OH)CH2NHCH3
CAS Number:
51-43-4
Molecular Weight:
183.20
Beilstein:
2368277
EC Number:
200-098-7
MDL number:
MFCD00002204
UNSPSC Code:
12352200
PubChem Substance ID:
24894545
NACRES:
NA.77

Quality Level

200

mp

215 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

CNC[C@H](O)c1ccc(O)c(O)c1

InChI

1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1

InChI key

UCTWMZQNUQWSLP-VIFPVBQESA-N

Gene Information

human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRA2A(150) , ADRA2B(151) , ADRA2C(152) , ADRB1(153) , ADRB2(154) , ADRB3(155)
rat ... Adra1a(29412) , Adra2a(25083) , Adrb1(24925) , Adrb2(24176) , Drd1a(24316) , Drd2(24318)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Adrenoceptor agonist.

Features and Benefits

This compound is featured on the α1-Adrenoceptors, α2-Adrenoceptors and β-Adrenoceptors pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Reconstitution

This product is only slightly soluble in water. Other sources state that it is soluble at 2 mg/mL in DMSO. The product solubility is tested at 50 mg/mL in 0.5 M HCl. This stock concentration can be diluted further in a buffer or medium to the required final concentration. In general, culture medium is buffered such that the final pH is not effected. The compound will remain in solution.

Pictograms

Skull and crossbones
GHS06

Signal Word

Danger

Hazard Statements

H301 + H331,H310

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

监管及禁止进口产品

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Anastasia Eskova et al.
Current biology : CB, 30(2), 298-303 (2020-01-07)
Color patterns are prominent features of many animals and are of high evolutionary relevance. In basal vertebrates, color patterns are composed of specialized pigment cells that arrange in multilayered mosaics in the skin. Zebrafish (Danio rerio), the preeminent model system
Mohit Kumar et al.
The Journal of biological chemistry, 295(32), 11275-11291 (2020-06-20)
Cardiac myosin-binding protein-C (cMyBP-C) is highly phosphorylated under basal conditions. However, its phosphorylation level is decreased in individuals with heart failure. The necessity of cMyBP-C phosphorylation for proper contractile function is well-established, but the physiological and pathological consequences of decreased
Nabil Mehaba et al.
Journal of dairy science, 104(1), 1099-1110 (2020-11-10)
Heat stress (HS) has a significant economic impact on the global dairy industry. However, the mechanisms by which HS negatively affects metabolism and milk synthesis in dairy ewes are not well defined. This study evaluated the production and metabolic variables
Eun-Min Kim et al.
PLoS neglected tropical diseases, 13(4), e0006843-e0006843 (2019-04-04)
Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear. Using the human cholangiocyte line H69, we investigated cell proliferation and gap junction protein expression after
Jonathan E Campbell et al.
American journal of physiology. Cell physiology, 300(1), C198-C209 (2010-10-15)
Glucocorticoids have been proposed to be both adipogenic and lipolytic in action within adipose tissue, although it is unknown whether these actions can occur simultaneously. Here we investigate both the in vitro and in vivo effects of corticosterone (Cort) on
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service