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Merck
CN

D8376

L-2,4-Diaminobutyric acid dihydrochloride

≥98% (TLC)

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About This Item

Linear Formula:
NH2CH2CH2CH(NH2)COOH · 2HCl
CAS Number:
Molecular Weight:
191.06
EC Number:
217-542-0
UNSPSC Code:
12352200
PubChem Substance ID:
Beilstein/REAXYS Number:
5763078
MDL number:
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Product Name

L-2,4-Diaminobutyric acid dihydrochloride, ≥98% (TLC)

InChI key

CKAAWCHIBBNLOJ-QTNFYWBSSA-N

InChI

1S/C4H10N2O2.2ClH/c5-2-1-3(6)4(7)8;;/h3H,1-2,5-6H2,(H,7,8);2*1H/t3-;;/m0../s1

SMILES string

Cl.Cl.NCC[C@H](N)C(O)=O

assay

≥98% (TLC)

mp

197-200 °C (dec.)

storage temp.

−20°C

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pictograms

CorrosionExclamation mark

signalword

Danger

Hazard Classifications

Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Sun-Young An et al.
The Journal of general and applied microbiology, 55(5), 339-343 (2009-11-27)
An actinobacterial strain, 2SbT, isolated from lichen was characterized taxonomically using a polyphasic approach. Strain 2SbT was Gram-positive, strictly aerobic, rod-shaped and non-motile. Phylogenetic analysis based on 16S rRNA gene sequence revealed that strain 2SbT was located in the genus
S A Banack et al.
Toxicon : official journal of the International Society on Toxinology, 56(6), 868-879 (2010-06-22)
The cyanobacterial neurotoxin beta-N-methylamino-L-alanine (BMAA) has been associated with certain forms of progressive neurodegenerative disease, including sporadic Amyotrophic Lateral Sclerosis and Alzheimer's disease. Reports of BMAA in cyanobacterial blooms from lakes, reservoirs, and other water resources continue to be made
Maria Hoernke et al.
Biochimica et biophysica acta, 1818(7), 1663-1672 (2012-03-22)
Basic amino acids play a key role in the binding of membrane associated proteins to negatively charged membranes. However, side chains of basic amino acids like lysine do not only provide a positive charge, but also a flexible hydrocarbon spacer
Thomas Krüger et al.
Toxicon : official journal of the International Society on Toxinology, 55(2-3), 547-557 (2009-10-15)
Since diverse taxa of cyanobacteria has been linked to biosynthesis of BMAA, a controversy has arisen about the detection of neurotoxic amino acids in cyanobacteria. In this context, a novel LC-MS/MS method was developed for the unambiguous determination of beta-N-methylamino-L-alanine
Michelle E Farkas et al.
Bioorganic & medicinal chemistry, 15(22), 6927-6936 (2007-09-18)
A hairpin polyamide-chlorambucil conjugate linked by alpha-diaminobutyric acid (alpha-DABA) has been shown to have interesting biological properties in cellular and small animal models. Remarkably, this new class of hairpin polyamides has not been previously characterized with regard to energetics and

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