Skip to Content
Merck
CN

C1605

Z-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone

powder, ≥95%

Synonym(s):

Z-VDVAD-FMK

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Linear Formula:
C32H46N5O11F
CAS Number:
210344-92-6
Molecular Weight:
695.73
NACRES:
NA.77
PubChem Substance ID:
329774898
UNSPSC Code:
12352209
MDL number:
MFCD03452881

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C32H46FN5O11/c1-17(2)26(30(44)34-19(5)28(42)35-21(23(39)15-33)13-24(40)47-6)37-29(43)22(14-25(41)48-7)36-31(45)27(18(3)4)38-32(46)49-16-20-11-9-8-10-12-20/h8-12,17-19,21-22,26-27H,13-16H2,1-7H3,(H,34,44)(H,35,42)(H,36,45)(H,37,43)(H,38,46)/t19-,21-,22-,26-,27-/m0/s1

SMILES string

COC(=O)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)OC)NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(=O)CF

InChI key

ANTIWMNLIROOQF-IREHUOSBSA-N

biological source

synthetic (organic)

assay

≥95%

form

powder

color

white

solubility

DMSO: soluble

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Gene Information

human ... CASP2(835)
mouse ... CASP2(12366)
rat ... CASP2(64314)

Biochem/physiol Actions

A cell-permeable inhibitor of caspase-2, which exhibits competitive and irreversible inhibition.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
SLCJ7619
SLBS5891
SLBN4838V
SLBF1345V
080M1515

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Mingxing Tian et al.
Veterinary microbiology, 244, 108648-108648 (2020-05-14)
Brucella is a facultative intracellular bacterium, dividing into smooth- and rough-type Brucella. Smooth-type Brucella can dissociate into rough mutants with cytotoxicity for macrophages during infection, which is critical for Brucella egress and dissemination. However, the mechanism of cytotoxicity infected by
Wolfgang W Quitschke
PloS one, 7(6), e39568-e39568 (2012-07-07)
Curcumin preparations typically contain a mixture of polyphenols, collectively referred to as curcuminoids. In addition to the primary component curcumin, they also contain smaller amounts of the co-extracted derivatives demethoxycurcumin and bisdemethoxycurcumin. Curcuminoids can be differentially solubilized in serum, which
Aitziber Buqué et al.
Molecular cancer, 11, 25-25 (2012-04-28)
Metastatic melanoma is a lethal skin cancer and its incidence is rising every year. It represents a challenge for oncologist, as the current treatment options are non-curative in the majority of cases; therefore, the effort to find and/or develop novel
L Gorvel et al.
Cell death & disease, 1, e34-e34 (2011-03-03)
Tropheryma whipplei, the etiological agent of Whipple's disease, is an intracellular bacterium that infects macrophages. We previously showed that infection of macrophages results in M2 polarization associated with induction of apoptosis and interleukin (IL)-16 secretion. In patients with Whipple's disease
Michael Tsabar et al.
Cell reports, 32(5), 107995-107995 (2020-08-07)
Cellular responses to stimuli can evolve over time, resulting in distinct early and late phases in response to a single signal. DNA damage induces a complex response that is largely orchestrated by the transcription factor p53, whose dynamics influence whether
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service