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Sigma-Aldrich

Bovine Aortic Endothelial Cells: BAOEC (Cryovial)

Synonym(s):

BAOEC cells

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About This Item

UNSPSC Code:
41106514
NACRES:
NA.81

biological source

bovine aorta (USDA-inspected cattle)

form

solid

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

karyotype

2n = 60

morphology

Endothelial

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

diabetes; cardiovascular diseases

shipped in

dry ice

storage temp.

−196°C

Related Categories

General description

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Bovine large artery endothelial cells (BAOEC) provide an excellent model system to study all aspects of cardiovascular function and disease, such as critical signaling pathways and mechanisms relevant to proper function of endothelia, including angiogenesis, permeability, flow adaptation, NO production, diabetes-related complications, etc., and search for beneficial modulators and delivery systems for therapeutic use, and to design scaffolds, surfaces and materials for tissue engineering and 3D modeling.

Cell Line Origin

Aorta

Application

cardiovascular function, studies on immune system and graft rejection, development of 3D endothelialized engineered tissues, drug discovery, stent-graft compatibility testing

Components

Bovine Endothelial Cell Growth Medium containing 10% FBS & 10% DMSO

Preparation Note

  • 2nd passage, >500,000 cells in Bovine Endothelial Cell Growth Medium containing 10% FBS & 10% DMSO
  • Can be cultured at least 16 doublings

Subculture Routine

Please refer to the BAOEC Culture Protocol.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Yuanyuan Zhang et al.
Cell reports, 36(8), 109616-109616 (2021-08-26)
Vascular development is a complex multistep process involving the coordination of cellular functions such as migration, proliferation, and differentiation. How mechanical forces generated by cells and transmission of these physical forces control vascular development is poorly understood. Using an endothelial-specific
Spencer G Miller et al.
JCI insight, 9(2) (2023-11-30)
Hyperuricemia is implicated in numerous pathologies, but the mechanisms underlying uric acid production are poorly understood. Using a combination of mouse studies, cell culture studies, and human serum samples, we sought to determine the cellular source of uric acid. In

Protocols

Bovine Aortic Endothelial Cells (BAOEC) Culture Protocol

Technical information for working with bovine aortic endothelial cells including thawing, subculturing and cryopreservation.

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