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14361C

SAFC

EX-CELL® CD CHO Serum-Free Medium for CHO Cells, Chemically Defined

Animal-component free, with hypoxanthine, with thymidine, without L-glutamine, liquid, sterile-filtered, suitable for cell culture

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Synonym(s):
EX-CELL® CD CHO Serum-Free Medium for CHO Cells, Chemically Defined
MDL number:
UNSPSC Code:
12352207
NACRES:
NA.75

Quality Level

description

for research or for further manufacturing use

sterility

sterile-filtered

form

liquid

technique(s)

cell culture | mammalian: suitable

components

NaHCO3: 2.10 g/L
phenol red: no
HEPES: no
glucose: 5.6 g/L

shipped in

ambient

storage temp.

2-8°C

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Application

EX-CELL CD CHO is a chemically defined, animal-component free, serum-free medium developed for the long-term growth of Chinese Hamster Ovary (CHO) cells and expression of antibodies or protein products in suspension cell culture. CHO suspension cultures can be subcultured directly into EX-CELL CD CHO from serum-supplemented or serum-free medium with little or no adaptation. EX-CELL CD CHO (Catalog No. 14361C) is formulated with hypoxanthine and thymidine, making it an appropriate medium for applications that do not require the selective pressure of a hypoxanthine/thymidine (HT)-deficient medium, such as CHO-K1 and Glutamine Synthetase (GS System) users.

Legal Information

EX-CELL is a registered trademark of Merck KGaA, Darmstadt, Germany
GS System is a trademark of Lonza Group Ltd.

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

常规特殊物品

Certificates of Analysis (COA)

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Andrew S Flies et al.
Science advances, 6(27) (2020-09-17)
Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their lifetime, compared to less than 10% for most species. In addition, devils are affected by two of the three known transmissible cancers in mammals. Immune checkpoint immunotherapy

Articles

A signal peptide is a 5-30 amino acid (aa) peptide present at the N-terminus of secretory proteins.

In the present study, we have identifi ed species-specifi c housekeeping genes (HKGs) for Chinese Hamster Ovary (CHO) cells using data from microarray gene expression profiling.

MGAT1 adds N-acetylglucosamine to the Man5GlcNAc2 (Man5) structure. Goh et al. reported increased sialylation after restoring MGAT1 function in MGAT1 deficient CHO cells.

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