All Photos(2)
Synonym(s):
Formic acid sodium salt
Linear Formula:
HCOONa
CAS Number:
Molecular Weight:
68.01
Beilstein:
3595134
EC Number:
MDL number:
UNSPSC Code:
12352300
eCl@ss:
39021901
PubChem Substance ID:
NACRES:
NA.55
grade
reagent grade
Quality Level
Assay
97%
form
crystalline powder
powder, crystals or granules
mp
259-262 °C (lit.)
solubility
water: soluble(lit.)
SMILES string
[Na+].[O-]C=O
InChI
1S/CH2O2.Na/c2-1-3;/h1H,(H,2,3);/q;+1/p-1
InChI key
HLBBKKJFGFRGMU-UHFFFAOYSA-M
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General description
Sodium formate is the colorless sodium salt of formic acid. It can be prepared by reacting formic acid with sodium hydroxide or carbonate. Its crystal structure has been investigated. Its crystals exhibit monoclinic-holohedral symmetry.
Application
- Engineering Redox Cofactor Balance for Improved 5-Methyltetrahydrofolate Production in Escherichia coli.: Sodium formate was used to manipulate redox cofactor balance, significantly enhancing the production of 5-methyltetrahydrofolate in E. coli, showcasing its potential in metabolic engineering applications (Yang et al., 2024).
- Intensity-dependent mass search for improving metabolite database matches in chemical isotope labeling LC-QTOF-MS-based metabolomics.: Sodium formate was utilized in isotope labeling for LC-QTOF-MS, improving metabolite database matching accuracy, thus enhancing metabolomics data quality (Li et al., 2023).
- High-Yield Synthesis of Enantiopure 1,2-Amino Alcohols from l-Phenylalanine via Linear and Divergent Enzymatic Cascades.: The study highlights sodium formate′s role in enzymatic cascades for the efficient synthesis of enantiopure amino alcohols, important intermediates in pharmaceutical synthesis (Corrado et al., 2022).
- UPLC-ESI-QTOF/MS and multivariate data analysis for blood plasma and serum metabolomics: effect of experimental artefacts and anticoagulant.: Sodium formate was used as a reference standard in UPLC-ESI-QTOF/MS, providing insights into minimizing experimental artefacts in blood plasma and serum metabolomics (Barri and Dragsted, 2013).
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Tissue Engineering: Part A, 16(02), 695-703 (2009)
The Crystal Structure of Sodium Formate, NaHCO21.
Zachariasen WH.
Journal of the American Chemical Society, 62(5), 1011-1013 (1940)
Formylation of Aryl Halides with Carbon Monoxide and Sodium Formate in the Presence of Palladium Catalyst.
Okano T, et al.
Bulletin of the Chemical Society of Japan, 67(8), 2329-2332 (1994)
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Journal of structural biology, 173(1), 46-56 (2010-08-05)
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Eagleson M.
Concise Encyclopedia Chemistry, 997-997 (1994)
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