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About This Item
Linear Formula:
Pt(NH3)2Cl2
CAS Number:
Molecular Weight:
300.05
UNSPSC Code:
41116107
NACRES:
NA.24
EC Number:
239-733-8
MDL number:
grade
pharmaceutical primary standard
API family
cisplatin
form
solid
shelf life
limited shelf life, expiry date on the label
manufacturer/tradename
BP
mp
270 °C (lit.)
application(s)
pharmaceutical
pharmaceutical small molecule
format
neat
storage temp.
2-8°C
SMILES string
N.N.Cl[Pt]Cl
InChI
1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChI key
LXZZYRPGZAFOLE-UHFFFAOYSA-L
General description
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Application
Cisplatin BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.
Also used in monographs such as:Cisplatin Injection
Also used in monographs such as:
Biochem/physiol Actions
Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.
Packaging
Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia
Other Notes
Sales restrictions may apply.
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signalword
Danger
target_organs
Respiratory system
Storage Class
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Hazard Classifications
Acute Tox. 2 Oral - Carc. 1B - Eye Irrit. 2 - Muta. 1B - Repr. 1B - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
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Shihong Ma et al.
Journal of cellular biochemistry, 121(5-6), 3256-3265 (2020-01-07)
Aberrant activation of the Hedgehog (Hh)/Gli pathway contributes to the tumorigenesis of several human cancers, including ovarian cancers. We investigated the function of SMO on cell growth, drug resistance, and invasive ability in A2780/DDP cells. Moreover, we also tested the
Ruiqian Li et al.
International urology and nephrology, 52(1), 187-196 (2019-12-13)
Cisplatin could result in a wide range of kidney injuries. During the pathogenetic process, the excessive generation of reactive oxygen species (ROS) induced by cisplatin has been regarded as the initial and critical role, by which DNA damage and cell
Xiaochen Wang et al.
Stem cells international, 2020, 8877577-8877577 (2020-09-05)
Esophageal squamous cell carcinoma (ESCC) is a frequent malignant tumor with low 5-year overall survival. Targeting ESCC tumor-initiating cells (TICs) may provide a new research avenue to achieve better therapeutic effects of ESCC. However, the identity and characteristics of ESCC
Global Trade Item Number
| SKU | GTIN |
|---|---|
| BP809 | 04061835275700 |