About This Item
species reactivity
human
packaging
pkg of 1 ea
manufacturer/tradename
Milliplex®
assay range
accuracy: 124%
(Neurogranin), accuracy: 84%
(FABP3), accuracy: 85%
(ApoE4), accuracy: 94%
(TREM2), accuracy: 97%
(Angiogenin), sensitivity: 11.0 pg/mL
(MinDC + 2SD; TREM2), sensitivity: 14.3 pg/mL
(MinDC + 2SD; FABP3), sensitivity: 162.8 pg/mL
(MinDC + 2SD; ApoE4), sensitivity: 19.9 pg/mL
(MinDC + 2SD; Neurogranin), sensitivity: 5.8 pg/mL
(MinDC + 2SD; Angiogenin), sensitivity: 6.1 pg/mL
(MinDC + 2SD; Ferritin), standard curve range: 15-50,000 pg/mL
(TREM2), standard curve range: 2-10,000 pg/mL
(Angiogenin), standard curve range: 24-100,000 pg/mL
(FABP3), standard curve range: 244-1,000,000 pg/mL
(ApoE4), standard curve range: 5-20,000 pg/mL
(Neurogranin), standard curve range: 6-25,000 pg/mL
(Ferritin), inter-assay cv: <10%
intra-assay cv: <5%
(Angiogenin), inter-assay cv: <10%
intra-assay cv: <5%
(FABP3), inter-assay cv: <10%
intra-assay cv: <5%
(TREM2), inter-assay cv: <15%
intra-assay cv: <10%
(Ferritin), inter-assay cv: <15%
intra-assay cv: <10%
(Neurogranin), inter-assay cv: <15%
intra-assay cv: <5%
(ApoE4)
technique(s)
multiplexing: suitable
input
cerebrospinal fluid(s) (CSF)
serum
cell culture supernatant
detection method
fluorometric (Luminex® xMAP® technology)
shipped in
wet ice
storage temp.
2-8°C
Application
Analytes included: Angiogenin, Apolipoprotein E4 (ApoE4), Fatty Acid Binding Protein 3 (FABP3), Ferritin, Neurogranin, Triggering Receptor Expressed on Myeloid Cells 2 (TREM2).
Note: When testing serum/plasma samples, Angiogenin and ApoE4 require a 1:200 dilution while FABP3, Ferritin, Neurogranin and TREM2 require a 1:10 dilution. These sets of analytes should not be multiplexed together and instead run as separate assays. If testing CSF samples, all analytes can be plexed together.
Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.
Disclaimer
Label License/Sticker for Assay Product:
By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.
Features and Benefits
- Comprehensive Pathway Coverage: Simultaneously quantify six critical neurological biomarkers spanning synaptic function, neuroinflammation, and lipid metabolism, providing a complete picture of neurodegeneration in a single assay.
- Dual-Fluid Versatility: Analyze both challenging CSF samples and accessible blood samples with exceptional sensitivity, enabling flexible study designs while addressing the critical need for blood-based neurological biomarkers.
- Research-Ready Reliability: Trust in consistent, reproducible results with < 5% intra-assay precision for most analytes and rigorous cross-reactivity testing, so your neuroscience discoveries are built on solid data foundations.
- Streamlined Neuroscience Workflow: Eliminate the complexity of multiple single-analyte assays with our comprehensive 6-plex format, accelerating your research timeline and maximizing your sample utility for breakthrough neurological insights.
General description
Legal Information
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
Regulatory Information
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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