MILLIPLEX^® Human Neuroscience Panel

Luminex is a registered trademark of Luminex Corp

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany

xMAP is a registered trademark of Luminex Corp

MILLIPLEX^® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 7 analytes in human serum, plasma, and cerebrospinal fluid (CSF).Analytes included: Angiotensinogen (AGT), Contactin-1, Fetuin A, Kallikrein-6, Osteopontin (OPN), soluble Superoxide Dismutase 1 (SOD1), soluble Superoxide Dismutase 2 (SOD2).Note: When testing serum/plasma samples, Fetuin A cannot be plexed with other analytes in this panel due to a required 1:40,000 dilution. The other 6 analytes can be assayed together as a multiplex when testing serum/plasma samples but Fetuin A must be tested as a singleplex.Assay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Comprehensive Oxidative Stress Assessment: Simultaneously quantify SOD1 and SOD2 antioxidant enzymes alongside inflammatory markers, providing complete oxidative stress profiling critical for understanding neurodegeneration mechanisms.
Cross-Disease Research Power: Leverage biomarkers relevant to ALS, Alzheimer′s disease, stroke, and multiple sclerosis in one panel, maximizing research impact and enabling comparative studies across neurological conditions.
Dual-Protocol Flexibility: Choose between overnight and 2-hour protocols to match your research timeline needs, with both delivering < 10% precision and excellent spike recovery across multiple sample types.
Multi-Sample Compatibility: Analyze CSF, serum, and plasma samples with optimized performance, maximizing research versatility and enabling comprehensive biomarker studies across different biological matrices.
Streamlined Neurological Research: Eliminate the complexity of seven separate assays with our integrated 7-plex format, accelerating your neuroscience discoveries while preserving precious samples for comprehensive protein profiling.

Oxidative damage is a hallmark of many neurological disorders. SOD1 and SOD2 neutralize reactive oxygen species and are implicated in conditions like ALS. Osteopontin rises in stroke and Alzheimer′s, reflecting inflammatory stress. Kallikrein-6 has emerged as a candidate marker for multiple sclerosis, while contactin-1, fetuin A, and angiotensinogen contribute to neuronal signaling, metabolic balance, and vascular regulation—each offering clues to disease progression.