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HMYOMAG-56K

MILLIPLEX® Human Myokine Panel

Configurable Human Myokine 15-Plex Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

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Product Name

MILLIPLEX® Human Myokine Panel, Configurable Human Myokine 15-Plex Panel

species reactivity

human

Quality Level

200

packaging

pkg of 1 ea

manufacturer/tradename

Milliplex®

assay range

accuracy: 100%
(Apelin)
accuracy: 92%
(IL-15)
accuracy: 96%
(FSTL-1)
accuracy: 97%
(LIF)
accuracy: 98%
(Oncostatin M (OSM))
sensitivity: 0.9 pg/mL
(MinDC+2SD; IL-6)
sensitivity: 14 pg/mL
(MinDC+2SD; FGF-21)
sensitivity: 259 pg/mL
(MinDC+2SD; Myostatin/GDF8)
sensitivity: 281 pg/mL
(MinDC+2SD; Irisin)
sensitivity: 4 pg/mL
(MinDC+2SD; LIF)
sensitivity: 40 pg/mL
(MinDC+2SD; Fractalkine/CX3CL1)
sensitivity: 5 pg/mL
(MinDC+2SD; IL-15)
sensitivity: 59 pg/mL
(MinDC+2SD; Osteocrin/Musclin)
sensitivity: 6 pg/mL
(MinDC+2SD; Oncostatin M (OSM))
sensitivity: 64 pg/mL
(MinDC+2SD; Apelin)
sensitivity: 7.5 ng/mL
(MinDC+2SD; Osteonectin (SPARC))
sensitivity: 737 pg/mL
(MinDC+2SD; Follistatin-like Protein 1 (FSTL1))
sensitivity: 815 pg/mL
(MinDC+2SD; Erythropoietin (EPO))
sensitivity: 9 pg/mL
(MinDC+2SD; BDNF)
sensitivity: 9.8 pg/mL
(MinDC+2SD; FABP3)
standard curve range: 0.6-2,400 pg/mL
(IL-6)
standard curve range: 10-40,000 pg/mL
(LIF)
standard curve range: 122-500,000 pg/mL
(Apelin)
standard curve range: 2-10,000 pg/mL
(BDNF)
standard curve range: 2-10,000 pg/mL
(IL-15)
standard curve range: 2-6,000 pg/mL
(Oncostatin M (OSM))
standard curve range: 24-100,000 pg/mL
(FABP3)
standard curve range: 244-1,000,000 pg/mL
(Erythropoietin (EPO))
standard curve range: 244-1,000,000 pg/mL
(Irisin)
standard curve range: 488-2,000,000 pg/mL
(Follistatin-like Protein 1 (FSTL1))
standard curve range: 488-2,000,000 pg/mL
(Myostatin/GDF8)
standard curve range: 49-200,000 pg/mL
(Fractalkine/CX3CL1)
standard curve range: 49-200,000 pg/mL
(Osteocrin/Musclin)
standard curve range: 5-20,000 pg/mL
(FGF-21)
standard curve range: 7-30,000 ng/mL
(Osteonectin (SPARC))
inter-assay cv: <15%
intra-assay cv: <10%
(Apelin)
inter-assay cv: <15%
intra-assay cv: <10%
(BDNF)
inter-assay cv: <15%
intra-assay cv: <10%
(Erythropoietin (EPO))
inter-assay cv: <15%
intra-assay cv: <10%
(FABP3)
inter-assay cv: <15%
intra-assay cv: <10%
(FGF-21)
inter-assay cv: <15%
intra-assay cv: <10%
(Follistatin-like Protein 1 (FSTL1))
inter-assay cv: <15%
intra-assay cv: <10%
(Fractalkine/CX3CL1)
inter-assay cv: <15%
intra-assay cv: <10%
(IL-15)
inter-assay cv: <15%
intra-assay cv: <10%
(IL-6)
inter-assay cv: <15%
intra-assay cv: <10%
(Irisin)
inter-assay cv: <15%
intra-assay cv: <10%
(LIF)
inter-assay cv: <15%
intra-assay cv: <10%
(Myostatin/GDF8)
inter-assay cv: <15%
intra-assay cv: <10%
(Oncostatin M (OSM))
inter-assay cv: <15%
intra-assay cv: <10%
(Osteocrin/Musclin)
inter-assay cv: <20%
intra-assay cv: <10%
(Osteonectin (SPARC))

technique(s)

multiplexing: suitable

input

serum
cell culture supernatant

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Related Categories

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance Simultaneously analyze up to 15 analytes in human serum, plasma, or cell/tissue culture supernatant samples.Analytes included: BDNF, Decorin, FSTL1, IL-6, IL-15, Irisin, LIF, MCP-1/CCL2, Myostatin, Osteocrin, Osteonectin, SPARC, TGF-β1, VEGF-A, and VEGF-DAssay Characteristics: Refer to kit protocol for assay cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.Label License/Sticker for Assay Product:By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:- Simultaneous quantification of 15 myokines and related biomarkers- Based on Luminex® xMAP® magnetic bead technology for high-throughput multiplexing- Compatible with serum, plasma, and cell/tissue culture supernatants or lysates- Wide dynamic range and high sensitivity for low-abundance targets- Includes all necessary reagents and standards for streamlined workflow- Rigorously tested for cross-reactivity, precision, and reproducibilityBenefits:- Enables comprehensive profiling of muscle-secreted cytokines and growth factors- Reduces sample volume requirements while maximizing data output- Saves time and cost compared to running multiple single-plex assays- Supports research in muscle metabolism, inflammation, and regenerative biology- Provides reliable, reproducible data for both basic and translational research

General description

FABP3, Myosin Light Chain 3 (MYL3), Cardiac Troponin I (cTnI), Cardiac Troponin T (cTnT), and Creatine Kinase Muscle (CKM) are key biomarkers of cardiac muscle injury and stress. These analytes help detect myocardial damage, assess cardiac function, and monitor cardiotoxicity, making them valuable in cardiovascular research and drug safety studies. Their combined measurement supports sensitive and specific evaluation of cardiac health in human samples.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Regulatory Information

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Kelly Ann Hutchinson et al.
Frontiers in physiology, 10, 1188-1188 (2019-10-28)
It is recommended that women accumulate 150-min of weekly moderate-intensity physical activity (MPA) when pregnant. Engaging in regular physical activity (PA) confers many health benefits to both the mother and the fetus. However, the molecular mechanisms by which these health
Ayla Karine Fortunato et al.
Journal of immunology research, 2018, 9675216-9675216 (2018-07-27)
Strength exercise is a strategy applied in sports and physical training processes. It may induce skeletal muscle hypertrophy. The hypertrophy is dependent on the eccentric muscle actions and on the inflammatory response. Here, we evaluate the physiological, immunological, and inflammatory
Xi He et al.
Signal transduction and targeted therapy, 6(1), 427-427 (2021-12-18)
Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism. In this study, we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-related diseases, and found new-onset insulin resistance, hyperglycemia, and decreased HDL-C in these
Joanna D C C Lima et al.
Journal of cachexia, sarcopenia and muscle, 10(5), 1045-1059 (2019-07-06)
Cachexia is a paraneoplastic syndrome related with poor prognosis. The tumour micro-environment contributes to systemic inflammation and increased oxidative stress as well as to fibrosis. The aim of the present study was to characterise the inflammatory circulating factors and tumour
Javier Diaz-Castro et al.
Frontiers in nutrition, 8, 761213-761213 (2021-11-09)
Practicing exercise is one of the best strategies to promote well-being and quality of life, however physical activity in schoolchildren and adolescents is developed in an unpredictable, intermittent way and in short periods. There are relatively few intervention studies investigating

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