HCYP3MAG-63K
MILLIPLEX® Human Cytokine/Chemokine Magnetic Bead Panel III - Immunology Multiplex Assay
Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.
Synonym(s):
Human cytokine multiplex kit, Luminex® human cytokine immunoassay, Millipore human cytokine panel
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About This Item
UNSPSC Code:
12161503
eCl@ss:
32161000
NACRES:
NA.84
Quality Level
species reactivity
human
manufacturer/tradename
Milliplex®
assay range
accuracy: 92-106%
standard curve range: 2.0-200,000 pg/mL
technique(s)
multiplexing: suitable
detection method
fluorometric (Luminex xMAP)
shipped in
wet ice
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General description
“Cytokine” is a general term used for a diverse group of soluble proteins and peptides which act as regulators under both normal and pathological conditions to modulate the functional activities of individual cells and tissues. These proteins also mediate direct interactions between cells and regulate processes taking place in the extracellular environment. The cytokine group of proteins includes lymphokines, interferons, colony stimulating factors and chemokines. Cytokine and chemokine research plays a significant role in achieving a deeper understanding of the immune system and its multi-faceted response to most antigens, as well as disease states such as inflammatory disease, allergic reactions, irritable bowel disease (IBD), sepsis, and cancer.
The MILLIPLEX® Human Cytokine / Chemokine Panel III enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression.
The
Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
The MILLIPLEX® Human Cytokine / Chemokine Panel III enables you to focus on the therapeutic potential of cytokines as well as the modulation of cytokine expression.
The
Luminex® xMAP® platform uses a magnetic bead immunoassay format for ideal speed and sensitivity to quantitate multiple analytes simultaneously, dramatically improving productivity while conserving valuable sample volume.
Panel Type: Cytokines/Chemokines
Specificity
Cross Reactivty
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Cross-reactivity between the antibodies and any of the other analytes in this panel is non-detectable or negligible.
Application
- Analytes: GCP2, HCC-1, I-TAC, IL-11, IL-29, Lymphotactin, M-CSF, MIG, MIP-3α, MIP-3β, NAP2
- Recommended Sample type: Serum, plasma, and cell culture supernatants
- Recommended Sample dilution: Neat plasma or serum. A 1:100 dilution is required for NAP-2 and HCC-1 for serum and plasma samples
- Assay Run Time: Overnight or two-hour primary incubation. For best results, an overnight incubation is recommended
- Research Category: Inflammation & Immunology
- Research Subcategory: Obesity, Metabolic Disorders, Inflammation & Autoimmune Mechanisms
Features and Benefits
Design your multiplex kit by choosing available analytes within this panel.
Packaging
Everything you need in a single kit.
Storage and Stability
Recommended storage for kit components is 2 - 8°C.
Other Notes
Please note: Sample Type must be selected when configuring this kit. HCC-1/CCL14a and NAP-2/CXCL7 cannot be plexed with other analytes for serum/plasma.
Sensitivity: Refer to kit protocol for sensitivities of individual cytokines/chemokines.
Legal Information
Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2
Target Organs
Respiratory Tract
Storage Class Code
10 - Combustible liquids
Regulatory Information
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Marie L Landry et al.
The Journal of infectious diseases, 217(6), 897-905 (2017-12-28)
Despite the high burden of respiratory infection and the importance of early and accurate diagnosis, there is no simple diagnostic test to rule in viral infection as a cause of respiratory symptoms. We performed RNA sequencing on human nasal epithelial
Kristen M Reeder et al.
Mucosal immunology, 11(5), 1352-1362 (2018-06-17)
Asthmatics sensitized to fungi are reported to have more severe asthma, yet the immunopathogenic pathways contributing to this severity have not been identified. In a pilot assessment of human asthmatics, those subjects sensitized to fungi demonstrated elevated levels of the
Alice L den Hertog et al.
PloS one, 10(6), e0129552-e0129552 (2015-06-27)
Many patients treated for tuberculosis (TB) in low and middle income countries are treated based on clinical suspicion without bacteriological confirmation. This is often due to lack of rapid simple accurate diagnostics and low healthcare provider confidence in the predictive
Junru Wu et al.
Cell reports. Medicine, 2(12), 100478-100478 (2022-01-15)
Trauma is a leading cause of death and morbidity worldwide. Here, we present the analysis of a longitudinal multi-omic dataset comprising clinical, cytokine, endotheliopathy biomarker, lipidome, metabolome, and proteome data from severely injured humans. A "systemic storm" pattern with release
Kavitha Kothur et al.
PloS one, 11(2), e0149411-e0149411 (2016-02-27)
Myelin oligodendrocyte glycoprotein antibody (MOG Ab) associated demyelination represents a subgroup of autoimmune demyelination that is separate from multiple sclerosis and aquaporin 4 IgG-positive NMO, and can have a relapsing course. Unlike NMO and MS, there is a paucity of
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