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ABN90P

Sigma-Aldrich

Anti-NeuN purified Antibody

from guinea pig, purified by affinity chromatography

Synonym(s):

NEUronal Nuclei, clone A60, NeuN

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100 μL
¥6,882.71

¥6,882.71

Estimated to ship on2025年5月26日Details

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100 μL
¥6,882.71

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

¥6,882.71

Estimated to ship on2025年5月26日Details

Sign In for Best Price
Request a Bulk Order

biological source

guinea pig

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human, rat, mouse

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

shipped in

wet ice

target post-translational modification

unmodified

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Show Differences

1 of 4

This Item
MAB377ABN91ABN90
抗-NeuN纯化抗体 from guinea pig, purified by affinity chromatography

ABN90P

抗-NeuN纯化抗体

抗NeuN抗体，克隆A60 clone A60, Chemicon®, from mouse

MAB377

抗NeuN抗体，克隆A60

抗-NeuN抗体 from chicken, purified by affinity chromatography

ABN91

抗-NeuN抗体

抗-NeuN抗体 serum, from guinea pig

ABN90

抗-NeuN抗体

biological source

guinea pig

biological source

mouse

biological source

chicken

biological source

guinea pig

Quality Level

100

Quality Level

100

Quality Level

100, 200

Quality Level

100

species reactivity

human, rat, mouse

species reactivity

avian, pig, chicken, human, rat, salamander, ferret, mouse

species reactivity

mouse, rat

species reactivity

rat, mouse

technique(s)

immunocytochemistry: suitable, western blot: suitable, immunohistochemistry: suitable (paraffin)

technique(s)

flow cytometry: suitable, immunocytochemistry: suitable, immunofluorescence: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable, western blot: suitable

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

technique(s)

immunocytochemistry: suitable, immunohistochemistry: suitable (paraffin), western blot: suitable

clone

polyclonal

clone

A60, monoclonal

clone

polyclonal

clone

polyclonal

General description

ABN90P is a Guinea Pig polyclonal version of the Anti-NeuN, clone A60 (MAB377), a highly characterized and cited mouse monoclonal antibody that specifically recognizes the DNA-binding, neuron-specific protein NeuN, which is present in most CNS and PNS neuronal cell types of all vertebrates tested. NeuN protein distributions are apparently restricted to neuronal nuclei, perikarya and some proximal neuronal processes in both fetal and adult brain although, some neurons fail to be recognized by NeuN at all ages: INL retinal cells, Cajal-Retzius cells, Purkinje cells, inferior olivary and dentate nucleus neurons, and sympathetic ganglion cells are some examples. Immunohistochemically detectable NeuN protein first appears at developmental timepoints that correspond with the withdrawal of the neuron from the cell cycle and/or with the initiation of terminal differentiation of the neuron. Immunoreactivity appears around E9.5 in the mouse neural tube and is extensive throughout the developing nervous system by E12.5. Strong nuclear staining suggests a nuclear regulatory protein function. No difference between protein isolated from purified nuclei and whole brain extract on immunoblots has been found.

Specificity

This antibody recognizes the N-terminus of NeuN.

Immunogen

Epitope: N-terminus
GST-tagged recombinant protein corresponding to the N-terminus of mouse NeuN.

Application

Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected NeuN in mouse frontal cortex tissue.

Immunocytochemistry Analysis: A 1:1,000-2,000 dilution from a representative lot detected NeuN in rat E18 cortex cells.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers
This Anti-NeuN purified Antibody is validated for use in Western Blotting, ICC, IHC(P) for the detection of NeuN purified.

Quality

Evaluated by Western Blot in mouse E16 brain tissue lysate.

Western Blot Analysis: A 1:1,000 dilution of this antibody detected NeuN on 10 µg of mouse E16 brain tissue lysate.

Target description

~48 kDa observed

Physical form

Antigen Affinity Purified
Purified guinea pig polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Mouse E16 brain tissue lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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