Product Compare

3-(Maleimido)propionic acid N-succinimidyl ester, BMPS, N-(3-Maleimidopropionyloxy)succinimide, N-Maleoyl-β-alanine N′-hydroxysuccinimide ester, N-Succinimidyl 3-maleimidopropionate

N-(3-Maleimidopropionyloxy)succinimide, N-Maleoyl-β-alanine N′-hydroxysuccinimide ester, N-Maleoyl-β-alanine N-hydroxysuccinimide ester, N-Succinimidyl 3-maleimidopropionate, BMPS

6-Maleimidocaproic acid N-succinimidyl ester, N-(ε-Maleimidocaproyloxy)succinimide, N-Succinimidyl 6-maleimidocaproate, EMCS

4-Maleimidobutyric acid N-succinimidyl ester, N-(γ-Maleimidobutyryloxy)succinimide, N-Succinimidyl 4-maleimidobutyrate, GMBS

CAS Number

55750-62-4

55750-63-5

80307-12-6

Molecular Formula

Empirical Formula (Hill Notation)

: C₁₁H₁₀N₂O₆

Empirical Formula (Hill Notation)

: C₁₁H₁₀N₂O₆

Empirical Formula (Hill Notation)

: C₁₄H₁₆N₂O₆

Empirical Formula (Hill Notation)

: C₁₂H₁₂N₂O₆

Molecular Weight

: 266.21

Molecular Weight

: 266.21

Molecular Weight

: 308.29

Molecular Weight

: 280.23

MDL Number

MFCD00043141

MFCD00043043

MFCD00036817

Quality Designations

200

100

Properties

Assay:

≥98.5% (HPLC)

Assay:

99%

Assay:

≥98.0% (HPLC)

Assay:

≥98.0% (HPLC)

functional group:

NHS ester

functional group:

NHS ester

functional group:

NHS ester

functional group:

NHS ester

InChI:

1S/C11H10N2O6/c14-7-1-2-8(15)12(7)6-5-11(18)19-13-9(16)3-4-10(13)17/h1-2H,3-6H2

InChI:

1S/C11H10N2O6/c14-7-1-2-8(15)12(7)6-5-11(18)19-13-9(16)3-4-10(13)17/h1-2H,3-6H2

InChI:

1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2

InChI:

1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

InChI key:

JKHVDAUOODACDU-UHFFFAOYSA-N

InChI key:

JKHVDAUOODACDU-UHFFFAOYSA-N

InChI key:

VLARLSIGSPVYHX-UHFFFAOYSA-N

InChI key:

PVGATNRYUYNBHO-UHFFFAOYSA-N

mp:

167-171 °C

mp:

168-170 °C (lit.)

mp:

67-73 °C
70-73 °C (lit.)

mp:

123-129 °C

form:

solid

form:

powder

form:

solid

form:

reaction suitability:

reagent type: linker

reaction suitability:

reagent type: linker

reaction suitability:

reagent type: linker

reaction suitability:

reagent type: linker

SMILES string:

O=C1CCC(N1OC(CCN2C(C=CC2=O)=O)=O)=O

SMILES string:

O=C1CCC(N1OC(CCN2C(C=CC2=O)=O)=O)=O

SMILES string:

O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O

SMILES string:

O=C1N(CCCC(ON2C(CCC2=O)=O)=O)C(C=C1)=O

storage temp.:

2-8°C

storage temp.:

2-8°C

storage temp.:

−20°C

storage temp.:

2-8°C

Quality Level:

Quality Level:

Quality Level:

Quality Level:

Usage and Safety

Application

Succinimidyl 3-maleimidopropionate (SMP, BMPS) is used as an aliphatic heterobifunctional crosslinker reagent. It is used for techniques such as the cross-linking of haptens to enzymes prior to enzyme immunoassays or fluorogenic substrates to peptidic antigens for use in fluorescence immunoassays.

6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thioether linkage buffered at pH 6.8 (6.5-7.0). Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Provides a 7-atom linker.

Risk and Safety

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Personal Protective Equipment:

dust mask type N95 (US), Eyeshields, Gloves

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Personal Protective Equipment:

dust mask type N95 (US), Eyeshields, Gloves

Pictograms: GHS07

Signal Word:

Warning

Hazard Statements: H315,H319,H335

Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications:

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs:

Respiratory system

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Personal Protective Equipment:

dust mask type N95 (US), Eyeshields, Gloves

Storage Class Code:

11 - Combustible Solids

WGK:

WGK 3

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Personal Protective Equipment:

dust mask type N95 (US), Eyeshields, Gloves