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Safety Information

SH2911

Sigma-Aldrich

MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock

B-Cell Activation

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1 EA
¥10,422.78

¥10,422.78

Estimated to ship on2025年7月23日Details

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1 EA
¥10,422.78

About This Item

UNSPSC Code:
41106609
NACRES:
NA.51

¥10,422.78

Estimated to ship on2025年7月23日Details

Request a Bulk OrderRequest more information

Quality Level

200

product line

MISSION®

storage temp.

−70°C

Gene Information

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1 of 4

This Item
SAB1401057SAB5701683SAB5701160
Anti- CD47 antibody produced in rabbit

SAB5700964

Anti- CD47 antibody produced in rabbit

Anti-CD47 antibody produced in mouse purified immunoglobulin, buffered aqueous solution

SAB1401057

Anti-CD47 antibody produced in mouse

Anti-CD74 antibody produced in rabbit

SAB5701683

Anti-CD74 antibody produced in rabbit

Anti- CD44 antibody produced in rabbit

SAB5701160

Anti- CD44 antibody produced in rabbit

biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

clone

monoclonal

clone

polyclonal

clone

monoclonal

clone

monoclonal

species reactivity

human, rat, mouse

species reactivity

human

species reactivity

human, rat, mouse

species reactivity

human, mouse, rat

Gene Information

human ... CD47(961)

Gene Information

human ... CD47(961)

Gene Information

human ... CD74(972)

Gene Information

human ... CD44(960)

UniProt accession no.

Q08722

UniProt accession no.

Q08722

UniProt accession no.

P04233

UniProt accession no.

P16070

form

liquid

form

buffered aqueous solution

form

liquid

form

liquid

General description

The clones are sequenced-verified shRNA lentiviral plasmids (pLKO.1-puro) provided as 50 μl bacterial glycerol stocks (Terrific Broth, carbenicillin at 100 μg/ml and 15% glycerol). The set comes in 96-well plates that are barcoded for simple identification. A CD containing RefSeq, gene description, gene symbol, clone ID, hairpin sequence, locus link, and plate map positions are provided with the gene family set.

Other Notes

Each MISSION shRNA clone is constructed within the lentivirus plasmid vector, pLKO.1-Puro, followed by transformation into Escherichia coli. The pLKO.1-Puro vector contains bacterial (ampicillin) and mammalian (puromycin) antibiotic resistance genes for selection of inserts in either bacterial or mammalian cell lines. Each clone set consists of an average of 3-5 constructs that have been designed against each target gene using a proprietary algorithm. Therefore, a range of knockdown efficiency, with at least one construct from each gene set being >70%, can be expected when using these clones. This allows one to examine the effect of loss of gene function over a large series of gene knockdown efficiencies. Each shRNA construct has been cloned and sequence verified to ensure a match to the target gene.
For a detailed listing of other available gene family sets, visit the gene family set website.
Number of Genes: 99, Number of Clones: 661
The exact gene and clone count at time of purchase may vary slightly as the TRC library is continually updated.

Legal Information

Use of this product is subject to one or more license agreements. For details, please see http://sigmaaldrich.com/missionlicense .
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Regulatory Information

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    Pavel Tolar et al.
    Immunological reviews, 221, 64-76 (2008-02-16)
    The binding of antigen to the B-cell receptor (BCR) induces BCR clustering and signaling cascades that lead to the activation of a variety of genes associated with B-cell activation. Over the last several years, our understanding of the molecular details
    Pierre Youinou
    Journal of autoimmunity, 28(2-3), 143-151 (2007-03-17)
    The interest for B cells has recently been revived. They normally play a role in the development, the regulation, as well as the activation of lymphoid architecture: they regulate dendritic cells and T-cell subsets function through cytokine production. Receptor editing

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