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Merck
CN

A9148

Ala-Ala-Phe p-nitroanilide

protease substrate

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About This Item

Empirical Formula (Hill Notation):
C21H25N5O5
CAS Number:
61043-41-2
Molecular Weight:
427.45
UNSPSC Code:
12352204
PubChem Substance ID:
24891399
MDL number:
MFCD00057666

Key Documents

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Product Name

Ala-Ala-Phe p-nitroanilide, protease substrate

InChI

1S/C21H25N5O5/c1-13(22)19(27)23-14(2)20(28)25-18(12-15-6-4-3-5-7-15)21(29)24-16-8-10-17(11-9-16)26(30)31/h3-11,13-14,18H,12,22H2,1-2H3,(H,23,27)(H,24,29)(H,25,28)

SMILES string

CC(N)C(=O)NC(C)C(=O)NC(Cc1ccccc1)C(=O)Nc2ccc(cc2)N(=O)=O

InChI key

RMYMOVDNWWDGFU-UHFFFAOYSA-N

assay

≥98% (HPLC)

form

powder

solubility

0.1% trifluoroacetic acid in acetonitrile: water (3:1): 1 mg/mL, clear, colorless

storage temp.

−20°C

Application

Substrate for chymotrypsin and tripeptidyl peptidase I.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCBG0095V
1417329V
1417329
1405440
096K1413

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Robert Dalton et al.
International journal of molecular sciences, 22(3) (2021-01-31)
Dendritic cells (DCs) are professional antigen presenting cells with a great capacity for cross-presentation of exogenous antigens from which robust anti-tumor immune responses ensue. However, this function is not always available and requires DCs to first be primed to induce

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