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A5758

Sigma-Aldrich

Antifoam Y-30 Emulsion

aqueous-silicone emulsion

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UNSPSC Code:
12161900

Quality Level

form

emulsion

contains

emulsifier

General description

Antifoam Y-30 Emulsion is an aqueous emulsion containing 30% active silicon. It contains non-ionic emulsifiers different from those in Antifoam Emulsions B and C. It is designed to control foam in aqueous systems.
Antifoam is also known as defoamer. It is a chemical additive that reduces and hinders the formation of foam in industrial process liquids. It is used to prevent formation of foam or is added to break foam that is already formed.

Application

Antifoam Y-30 Emulsion is used for the following applications:
  • Chemostat cultivation.
  • Cultivation conditions, such as Fed-batch fermentation.
  • Bacterial strains and growth conditions (used in all aerosol experiments).

Other Notes

A 30% aqueous emulsion of Antifoam A concentrate.

Linkage

More easily dispersed in aqueous systems than Antifoam A concentrate.

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Has there been a name change for Antifoam Y-30 Emulsion, Product A5758?

    Yes. The product was formerly listed under the name "Antifoam A Emulsion".  Although there has been a name change, there is no change in the composition of the antifoam. It is the same product.

  6. What is Antifoam Y-30 emulsion?

    Antifoam Y-30 emulsion,a Dow-Corning product, is a 30% active silicone emulsion, whose usage is intended for controlling foam in aqueous systems. The composition of the antifoam is considered proprietary by the manufacturer.  However, the emulsifier type is described as nonionic.

  7. How can Product No. A5758, Antifoam Y-30 Emulsion be used?

    This antifoam can be diluted with water. It is effective at low concentrations (1-100 ppm is the usual range to use). Trials can start at 50 ppm (active silicone), and amounts may be reduced to where the level of foam control is desired. The product should be agitated before use.

  8. Can Antifoam Y-30 Emulsion, Product A5758, be autoclaved?

    Dow Corning® does not recommend that the emulsion be autoclaved since autoclaving can adversely affect the product.  

  9. What is the difference between product A5758, Antifoam Y-30 emulsion and product A6457?

    Product A6457, a molecular biology reagent, has been function-tested by Sigma for use in bacterial fermentation. Product A5758 has not been tested in this application by Sigma.

  10. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Sarah J Routledge et al.
Methods in molecular biology (Clifton, N.J.), 866, 87-97 (2012-03-29)
Pichia pastoris is a widely used host for recombinant protein production. The foaming associated with culturing it on a large scale is commonly prevented by the addition of chemical antifoaming agents or "antifoams." Unexpectedly, the addition of a range of
Adrien Pagnier et al.
Proceedings of the National Academy of Sciences of the United States of America, 113(1), 104-109 (2015-12-25)
The synthesis and assembly of the active site [FeFe] unit of [FeFe]-hydrogenases require at least three maturases. The radical S-adenosyl-l-methionine HydG, the best characterized of these proteins, is responsible for the synthesis of the hydrogenase CO and CN(-) ligands from
Modeling of growth and energy metabolism of Pichia pastoris producing a fusion protein.
M. Jahic, J.C. Rotticci-Mulder, M. Martinelle, K. Hult, S-O. Enfors
Bioprocess and Biosystems Engineering, 24, 385-393 (2002)
Mehmedalija Jahic et al.
Microbial cell factories, 2(1), 6-6 (2003-07-23)
BACKGROUND: A temperature limited fed-batch (TLFB) technique is described and used for Pichia pastoris Mut+ strain cultures and compared with the traditional methanol limited fed-batch (MLFB) technique. A recombinant fusion protein composed of a cellulose-binding module (CBM) from Neocallimastix patriciarum
N Meinander et al.
Microbiology (Reading, England), 142 ( Pt 1), 165-172 (1996-01-01)
Recombinant Saccharomyces cerevisiae harbouring the xylose reductase (XR) gene XYL1 from Pichia stipitis was grown in anoxic chemostat culture at two different dilution rates. At each dilution rate a transient experiment, encompassing a shift in the sugar content of the

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