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Merck
CN

56963

Atto Thio12

BioReagent, suitable for fluorescence

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About This Item

MDL number:
MFCD29074179
UNSPSC Code:
12352108
PubChem Substance ID:
329758254
NACRES:
NA.32

Key Documents

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Product Name

Atto Thio12, BioReagent, suitable for fluorescence

SMILES string

[O-]Cl(=O)(=O)=O.CN(C)c1ccc2c(SC3=C\C(C=CC3=C2c4ccccc4C(=O)N(C)CCCC(O)=O)=[N+](\C)C)c1

InChI

1S/C29H31N3O3S.ClHO4/c1-30(2)19-12-14-23-25(17-19)36-26-18-20(31(3)4)13-15-24(26)28(23)21-9-6-7-10-22(21)29(35)32(5)16-8-11-27(33)34;2-1(3,4)5/h6-7,9-10,12-15,17-18H,8,11,16H2,1-5H3;(H,2,3,4,5)

InChI key

CNHBWUJLSIHMSI-UHFFFAOYSA-N

product line

BioReagent

assay

≥90% (HPLC)

form

solid

manufacturer/tradename

ATTO-TEC GmbH

λ

in ethanol (with 0.1% trifluoroacetic acid)

UV absorption

λ: 575-581 nm Amax

suitability

suitable for fluorescence

storage temp.

−20°C

Application

Atto Thio12 is a new label closely related to the well-known rhodamines for coupling to biomolecules such as DNA, RNA or proteins. The characteristic feature of the label is high yield of triplet formation. The dye is moderately hydrophilic.

Legal Information

This product is for Research use only. In case of intended commercialization, please contact the IP-holder (ATTO-TEC GmbH, Germany) for licensing.

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
BCCL5718
BCCH4077
1467047V

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Marcia Levitus et al.
Quarterly reviews of biophysics, 44(1), 123-151 (2010-11-27)
The breakthroughs in single molecule spectroscopy of the last decade and the recent advances in super resolution microscopy have boosted the popularity of cyanine dyes in biophysical research. These applications have motivated the investigation of the reactions and relaxation processes
Andriy Chmyrov et al.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 7(11), 1378-1385 (2008-10-30)
Photo-induced switching of dyes into dark, long-lived states, such as a triplet state, has recently gained increasing interest, as a means to achieve ultra-high optical resolution. Additionally, these long lived states are often highly environment-sensitive and their photodynamics can thus

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