Innovations in process analytical technologies (PAT) are helping to provide more comprehensive and earlier product and process monitoring and control capabilities. In this talk, we will focus on an automated sampling system and its utilization in perfusion cell culture for upstream process development. We will demonstrate an increased frequency of data acquisition for the online measurement of CPPs and automation of a sample processing workflow to reduce the time to measure CQAs in perfusion cultures. Finally, we will discuss the impact of automated sampling to reduce manual labor, accelerate access to analytical data, and reduce risk in the upstream process.
In this webinar, you will learn:
- The benefits of automated sampling to the upstream lab
- How automated sampling can accelerate access to critical process parameters (CPPs) and critical quality attributes (CQAs)
- How automated sampling complements in-line technologies to expand the capabilities for automated measurement of CPPs and CQAs
Speaker
Allyson Caron
Merck
R&D Manager, Upstream Bioprocessing Applications
Allyson Caron is an R&D Manager in the BioProcessing Single-Use & Integrated Systems team at Merck. She joined the company in 2015 after completing her B.S. in chemical and biological engineering from Tufts University. Allyson has been involved with multiple projects to develop and commercialize new technologies with a focus on upstream cell culture and, more recently, on process analytical technologies (PAT). Today she leads a team of scientists and engineers who provide applications work for product development. Allyson also holds an M.S. in biotechnology from Johns Hopkins University.
Pharma and biopharma manufacturing
- Pharma and biopharma manufacturing
Duration:1h
Language:English
Session 1:presented October 27, 2022
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