生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
形式
buffered aqueous solution
种属反应性
mouse, human, rat
技术
immunofluorescence: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... SUMO1(7341)
一般描述
SUMO1 (small ubiquitin-related modifier) is also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin. It is located in the nucleus. It is located in chromosome 2q33.
SUMO1 (small ubiquitin-related modifier) is also called as Pic1 (inner centromere protein-related protein), Ubl1 (ubiquitin-like protein), hSmt3 (human homolog 3), or sentrin. It is located in the nucleus. SUMO1 gene is located on human chromosome 2q33.
免疫原
a 14 amino acid peptide from near the amino-terminus of human sumo.
生化/生理作用
Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It involves in mitochondrial fission.
Suppressing SUMO1 (small ubiquitin-related modifier) stops multiplication and induces apoptosis of gastric cancer SGC-7901 cells. It is essential for HCV (hepatitis C virus) replication. Deletion of SUMO1 blocks the aggregation of lipid droplets. It is involved in mitochondrial fission.
联系
The action of this antibody can be blocked using blocking peptide SBP3969.
外形
Solution in phosphate buffered saline containing 0.02% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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相关产品
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
SUMO1 depletion prevents lipid droplet accumulation and HCV replication
Akil A, et al.
Archives of Virology, 161(1), 141-148 (2016)
Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission
Harder Z, et al.
Current Biology, 14(4), 340-345 (2004)
The genetic basis of cleft lip and cleft palate
Veros C, et al.
Aristotle University Medical Journal, 43 (2016)
SUMO-1 Gene Silencing Inhibits Proliferation and Promotes Apoptosis of Human Gastric Cancer SGC-7901 Cells
Jin L, et al.
Cellular Physiology and Biochemistry, 41(3), 987-998 (2017)
The nucleoporin RanBP2 has SUMO1 E3 ligase activity
Pichler A, et al.
Cell, 108(1), 109-120 (2002)
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