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Merck
CN
所有图片(1)

文件

8.51029

Sigma-Aldrich

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms)

Novabiochem®

别名:

N-Biotinyl-NH-(PEG)₂-COOH . DIPEA (20 atoms), O-(N-Biotinyl-3-aminopropyl)-O′-(N-glutaryl-3-aminopropyl)-diethyleneglycol · DIPEA

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About This Item

经验公式(希尔记法):
C25H44N4O8S · xC8H19N
分子量:
560.70
UNSPSC代码:
12352106
NACRES:
NA.22

质量水平

产品线

Novabiochem®

检测方案

≥95.0% (HPLC)
≥98% (TLC)

形式

powder

反应适用性

reaction type: Biotinylations

制造商/商品名称

Novabiochem®

mp

131-136 °C

应用

peptide synthesis

储存温度

2-8°C

一般描述

The use of this novel biotin derivative incorporates a hydrophilic 20 atom PEG spacer between the peptide and biotin. This not only greatly improves the solubility of the resultant peptide, but reduces steric hindrance between the peptide and biotin, leading to better avidin binding and higher biological activity. The biotin-PEG derivative can be easily incorporated using any standard coupling method as the final step in SPPS, immediately prior to cleavage of the peptide from the resin.

Associated Protocols and Technical Articles

Biotinylation Reagents for Peptide Synthesis

联系

Replaces: 01-63-0133

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Purity (TLC(CMA2)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)
Solubility (50 mg in 1 ml NMP): clearly soluble

To see the solvent systems used for TLC of Novabiochem® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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商品

Biotin-labelled peptides find applications in immunology and histochemistry for affinity purification and receptor localization.

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