PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
别名:
AMPK, HAMPKb
物种:
Human PRKAB1 (5564), Mouse Prkab1 (19079), Rat Prkab1 (83803), Horse PRKAB1 (100034094), sheep PRKAB1 (101107899), chicken PRKAB1 (416986), domestic cat PRKAB1 (101094051), naked mole-rat Prkab1 (101705863), cow PRKAB1 (534107), domestic guinea pig Prkab1 (100719458)
UniProtKB ID:
基因ID:
- Human(5564) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
- Mouse(19079) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Rat(83803) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Horse(100034094) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- sheep(101107899) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- chicken(416986) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic cat(101094051) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- naked mole-rat(101705863) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- cow(534107) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic guinea pig(100719458) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- dog(486295) protein kinase, AMP-activated, beta 1 non-catalytic subunit
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
货号
说明
物种反应性
应用
Anti-PRKAB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-AMPKβ1-S108 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
western blot
Anti-phospho-AMPK β1 (pSer181) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRKAB1 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
货号
说明
物种
AMPK (α1, β1, γ1) 蛋白，活性，10 µg, Active, recombinant, human AMPK (α1, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα1, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
物种
human
AMPK (α2, β1, γ1) Protein, active, 10 µg, Active, recombinant, human AMPK (α2, β1, γ1) holoenzyme, comprised of full length N-terminal 6His-tagged AMPKα2, full length untagged AMPKβ1 & full length untagged AMPKγ1. For use in Kinase Assays.,
物种
human
AMPK (α1/β1/γ1)，活性，His标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
esiRNA
货号
说明
物种