PDE6G
phosphodiesterase 6G, cGMP-specific, rod, gamma
PDEG, RP57
Human PDE6G (5148), Mouse Pde6g (18588), Rat Pde6g (688297), naked mole-rat Pde6g (101705352), domestic guinea pig Pde6g (100135595), domestic cat PDE6G (101088443), cow PDE6G (281977), sheep PDE6G (101117520), dog PDE6G (403911), Zebrafish pde6g (554700)
- Human(5148) Summary: This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]
- Mouse(18588) phosphodiesterase 6G, cGMP-specific, rod, gamma
- Rat(688297) phosphodiesterase 6G, cGMP-specific, rod, gamma
- naked mole-rat(101705352) phosphodiesterase 6G, cGMP-specific, rod, gamma
- domestic guinea pig(100135595) phosphodiesterase 6G, cGMP-specific, rod, gamma
- domestic cat(101088443) phosphodiesterase 6G, cGMP-specific, rod, gamma
- cow(281977) phosphodiesterase 6G, cGMP-specific, rod, gamma
- sheep(101117520) phosphodiesterase 6G, cGMP-specific, rod, gamma
- dog(403911) phosphodiesterase 6G, cGMP-specific, rod, gamma
- Zebrafish(554700) phosphodiesterase 6G, cGMP-specific, rod, gamma
- chicken(395091) phosphodiesterase 6G, cGMP-specific, rod, gamma
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