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Merck
CN

CYP2C8

cytochrome P450, family 2, subfamily C, polypeptide 8

别名:
CPC8, CYPIIC8, MP-12/MP-20
物种:
UniProtKB ID:
基因ID:
  • Human(1558) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]

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Antibodies

货号
说明
物种反应性
应用
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-Cytochrome P450 2C8 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot
Anti-CYP2C8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
Anti-CYP2C8 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物种反应性
human
应用
ELISA
western blot
Anti-CYP450 Pan 2C Antibody, serum, Chemicon®,
物种反应性
human
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
特非那定, ,
物种
mouse, rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CYP2C8,
物种
human