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Merck
CN

CCNA1

cyclin A1

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(8900) Summary: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. This cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(12427) cyclin A1
  • Rat(295052) cyclin A1
  • sheep(101105579) cyclin A1
  • chicken(418901) cyclin A1
  • Zebrafish(404206) cyclin A1
  • cow(521939) cyclin A1
  • domestic cat(101085426) cyclin A1
  • domestic guinea pig(100716489) cyclin A1
  • dog(477302) cyclin A1
  • naked mole-rat(101718933) cyclin A1

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Antibodies

货号
说明
物种反应性
应用
Anti-Cyclin A antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-Cyclin A1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
immunohistochemistry

western blot
Monoclonal Anti-CCNA1 antibody produced in mouse, clone 4A11-5B5, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
proximity ligation assay

western blot
Anti-CCNA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence
Anti-CCNA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry

Proteins

货号
说明
物种
CDK2/CyclinA1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Ccna1,
物种
mouse
MISSION® esiRNA, targeting human CCNA1,
物种
human