CASP10
caspase 10, apoptosis-related cysteine peptidase
别名:
ALPS2, FLICE2, MCH4
物种:
Human CASP10 (843), cow CASP10 (100848685), chicken CASP10 (424081), domestic cat CASP10 (101085995), naked mole-rat Casp10 (101712620), domestic guinea pig Casp10 (100717714), Horse CASP10 (100068201), dog CASP10 (488472)
UniProtKB ID:
基因ID:
- Human(843) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
- cow(100848685) caspase 10, apoptosis-related cysteine peptidase
- chicken(424081) caspase 10, apoptosis-related cysteine peptidase
- domestic cat(101085995) caspase 10, apoptosis-related cysteine peptidase
- naked mole-rat(101712620) caspase 10, apoptosis-related cysteine peptidase
- domestic guinea pig(100717714) caspase 10, apoptosis-related cysteine peptidase
- Horse(100068201) caspase 10, apoptosis-related cysteine peptidase
- dog(488472) caspase 10, apoptosis-related cysteine peptidase
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Antibodies
货号
说明
物种反应性
应用
Anti-CASP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
western blot
western blot
Anti-Caspase-10 Antibody, from rabbit, purified by affinity chromatography,
物种反应性
human
应用
western blot
Monoclonal Anti-CASP10 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
ELISA
proximity ligation assay
proximity ligation assay
Anti-CASP10 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
western blot
Anti-CASP10 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
货号
说明
物种
Proteins
货号
说明
物种
Caspase 10 human, >90% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, 8,000 units/mg protein (Bradford),
物种
human
esiRNA
货号
说明
物种