biological source
bovine pancreas
form
liquid
specific activity
1500 units/mL
3000 units/mL
concentration
20 mg/mL in Tris buffer
technique(s)
DNA purification: suitable
storage temp.
room temp
Quality Level
Gene Information
bovine ... RNASE1(282340), RNASE1(280930)
Application
RNase A溶液可用于：
- Hep-2细胞的细胞凋亡检测
- 甲基化DNA的比色定量
- DNA 和RNA的提取
- DNA梯状分析
- 细胞周期分析
- 作为磷酸盐缓冲液（PBS）的成分，用于培养流式细胞仪的细胞。
Biochem/physiol Actions
核糖核酸酶 A 或牛胰核糖核酸酶 A (RNase A) 是一种内切核糖核酸酶，具有在嘧啶残基 3′ 侧切割单链 RNA 的特定能力。这种含有 124 个氨基酸的核酸内切酶在基因复制、细胞代谢和癌症治疗中发挥着关键作用。它的过度表达与多种癌症密切相关。因此，RNase A有可能成为一种很有前景的诊断恶性肿瘤的新生物标志物，也可作为新药研发的特异性靶点。RNase A 通常用于分离质粒 DNA。
General description
核糖核酸酶 A (RNase A) 是一种由三个 α 螺旋和七条 β 链组成的两个亚基的蛋白质” 是重要的典型结构域交换蛋白质。它以其多样的寡聚态而闻名。RNase A 家族的名称源自牛胰腺 RNase A，是脊椎动物特有的。在人类中，该家族包含八个功能成员，显示了其生物学相关性。
用于 GenErude™ 试剂盒中的样品制备。
用于 GenErude™ 试剂盒中的样品制备。
Preparation Note
有关使用要求，请参阅试剂盒操作步骤。
Legal Information
GenElute is a trademark of Sigma-Aldrich Co. LLC
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
低风险生物材料
此项目有
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