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Anti-LRP1 Antibody, Intracellular domain serum, from rabbit

Sigma-Aldrich

ABN1018

Anti-LRP1 Antibody, Intracellular domain

Anti-LRP-1 Antibody, clone 11H4 clone 11H4, from mouse

Sigma-Aldrich

MABS2001M

Anti-LRP-1 Antibody, clone 11H4

Anti-LRP1 Antibody, 85 kDa subunit Antibody, clone 6F8 clone 6F8, from mouse

Sigma-Aldrich

MABN1796

Anti-LRP1 Antibody, 85 kDa subunit Antibody, clone 6F8

Monoclonal Anti-LRP1 antibody produced in mouse ~1.0 mg/mL, clone LRP1-11, purified immunoglobulin, buffered aqueous solution

Sigma-Aldrich

L2420

Monoclonal Anti-LRP1 antibody produced in mouse

serum, from rabbit

clone 11H4, from mouse

clone 6F8, from mouse

~1.0 mg/mL, clone LRP1-11, purified immunoglobulin, buffered aqueous solution

ABN1018

Anti-LRP1 Antibody, Intracellular domain

MABS2001M

Anti-LRP-1 Antibody, clone 11H4

MABN1796

Anti-LRP1 Antibody, 85 kDa subunit Antibody, clone 6F8

L2420

Monoclonal Anti-LRP1 antibody produced in mouse

说明

别名

Prolow-density lipoprotein receptor-related protein 1, A2MR, Alpha-2-macroglobulin receptor, APOER, Apolipoprotein E receptor, CD91, LRP-1, LRP-85, LRPICD

Prolow-density lipoprotein receptor-related protein 1, Alpha-2-macroglobulin receptor1, A2MR, Apolipoprotein E receptor, APOER, CD91

Prolow-density lipoprotein receptor-related protein 1, A2MR, Alpha-2-macroglobulin receptor, APER, Apolipoprotein E receptor, CD19, Low-density lipoprotein receptor-related protein 1 85 kDa subunit, LRP-85

Anti-A2MR, Anti-APOER, Anti-APR, Anti-Apolipoprotein E receptor, Anti-Apolipoprotein receptor, Anti-CD91, Anti-LRP, Anti-Lipoprotein receptor-related protein, Anti-Low density lipoprotein receptor-related protein 1

质量目标

100

200

属性

NCBI accession no.:

NP_002323

NCBI accession no.:

NP_002323

NCBI accession no.:

NP_002323
NP_032538.2

NCBI accession no.:

UniProt accession no.:

Q07954

UniProt accession no.:

Q07954

UniProt accession no.:

Q07954
Q91ZX7

UniProt accession no.:

Q07954

antibody form:

serum

antibody form:

purified antibody

antibody form:

purified immunoglobulin

antibody form:

purified immunoglobulin

biological source:

rabbit

biological source:

mouse

biological source:

mouse

biological source:

mouse

clone:

polyclonal

clone:

11H4, monoclonal

clone:

6F8, monoclonal

clone:

LRP1-11, monoclonal

concentration:

~1.0 mg/mL

conjugate:

unconjugated

Gene Information:

human ... LRP1(4035)

Gene Information:

human ... LRP1(4035)

Gene Information:

human ... LRP1(4035)

Gene Information:

human ... LRP1(4035)
mouse ... Lrp1(16971) , Lrp1(299858)

shipped in:

ambient

shipped in:

dry ice

isotype:

IgG1κ

isotype:

IgG1κ

isotype:

IgG1

mol wt:

antigen ~500 kDa

packaging:

antibody small pack of 25 μg

packaging:

form:

buffered aqueous solution

target post-translational modification:

unmodified

target post-translational modification:

unmodified

target post-translational modification:

unmodified

target post-translational modification:

unmodified

antibody product type:

primary antibodies

antibody product type:

primary antibodies

antibody product type:

primary antibodies

antibody product type:

primary antibodies

species reactivity (predicted by homology):

human (based on 100% sequence homology), rat (based on 100% sequence homology)

species reactivity (predicted by homology):

species reactivity:

mouse

species reactivity:

rat, mouse, human

species reactivity:

human, mouse

species reactivity:

human, rat, mouse

storage temp.:

−20°C

technique(s):

western blot: suitable

technique(s):

immunocytochemistry: suitable
immunohistochemistry: suitable (paraffin)
immunoprecipitation (IP): suitable
western blot: suitable

technique(s):

ELISA: suitable
western blot: suitable

technique(s):

indirect immunofluorescence: suitable
western blot: 1-2 μg/mL

Quality Level:

Quality Level:

Quality Level:

Quality Level:

用途与安全性

应用

Anti-LRP1 Antibody, Intracellular domain is an antibody against LRP1 for use in Western Blotting.Research Category
NeuroscienceResearch Sub Category
Neurodegenerative DiseasesWestern Blotting Analysis: A representative lot detected the LRP-85 target band in NIH/3T3 cell lysate, as well as in mouse brain and liver homogenates (Courtesy of Professor Nicola Zambrano, University of Naples Federico II, Italy).
Western Blotting Analysis: A representative lot detected a decreased LRP-85 target band in lysates from LRP1 shRNA-treated NIH/3T3 cells (Courtesy of Professor Nicola Zambrano, University of Naples Federico II, Italy).

Anti-LRP-1, clone 11H4, Cat. No. MABS2001, is a mouse monoclonal antibody that detects Prolow-density lipoprotein receptor-related protein 1 in human, mouse, and rat and has been tested for use in Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blotting and Immunoprecipitation.Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected LRP-1 in human liver tissue.

Immunoprecipitation Analysis: A representative lot detected LRP-1 in Immunoprecipitation applications (Nieves, E.C., et. al. (2010). J Biol Chem. 285(17):12595-603).

Western Blotting Analysis: A representative lot detected LRP-1 in Western Blotting applications (Spoelgen, R., et. al. (2009). Neuroscience. 158(4):1460-8; Lleó, A., et. al. (2005). J Biol Chem. 280(29):27303-9; Campana, W.M., et. al. (2006). J Nuerosci. 26(43):11197-207).

Immunocytochemistry Analysis: A representative lot detected LRP-1 in Immunocytochemistry applications (Lleó, A., et. al. (2005). J Biol Chem. 280(29):27303-9).

Immunohistochemistry Analysis: A representative lot detected LRP-1 in Immunohistochemistry applications (Campana, W.M., et. al. (2006). J Nuerosci. 26(43):11197-207).
Research Category
Signaling

Anti-LRP1, 85 kDa subunit, clone 6F8, Cat. No. MABN1796, is a highly specific mouse monoclonal antibody that targets LRP1 85 kDa subunit and has been tested in ELISA and Western Blotting.Research Category
NeuroscienceWestern Blotting Analysis: 0.5 µg/mL from a representative lot detected LRP1 85 kDa subunit in 10 µg of mouse hippocampus tissue lysate.

ELISA Analysis: A representative lot was employed as the capture antibody for the detection of LRP1 in different human brain regions by sandwich ELISA. a strong positive correlation between LRP1 and PSD95 regional distribution was observed (Shinohara, M., et al. (2013). Acta Neuropathol. 125(4):535-547).

Western Blotting Analysis: A representative lot detected siRNA-mediated LRP1 knockdown in human brain vascular pericytes (Casey, C.S., et al. 2015. J. Biol. Chem. 290(22):14208-14217).

Note: The use of 5% skim milk as the blocking agent and 1-2 hr instead of overnight primary incubation time is recommended for Western blotting application to minimize non-specific background.

Monoclonal Anti-LRP1 antibody produced in mouse has been used in:

immunoblotting
enzyme linked immunosorbent assay
immunofluorescence

风险与安全

Storage Class Code:

12 - Non Combustible Liquids

WGK:

WGK 1

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Storage Class Code:

12 - Non Combustible Liquids

WGK:

WGK 1

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Storage Class Code:

12 - Non Combustible Liquids

WGK:

WGK 1

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable

Storage Class Code:

10 - Combustible liquids

Flash Point(F):

Not applicable

Flash Point(C):

Not applicable