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Merck
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PRKAG3

protein kinase, AMP-activated, gamma 3 non-catalytic subunit

别名:
AMPKG3
物种:
UniProtKB ID:
基因ID:
  • Human(53632) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
  • Mouse(241113) protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
  • Rat(301518) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • cow(511961) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • domestic guinea pig(100724729) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • chicken(424208) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • naked mole-rat(101699667) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • Domestic Rabbit(100352581) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • domestic cat(101092204) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • sheep(100142674) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • Goat(100861301) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • Horse(100034099) protein kinase, AMP-activated, gamma 3 non-catalytic subunit
  • dog(488526) protein kinase, AMP-activated, gamma 3 non-catalytic subunit

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Proteins

货号
说明
物种
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRKAG3,
物种
human
MISSION® esiRNA, targeting mouse Prkag3,
物种
mouse