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Merck
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PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit

别名:
AMPKG
物种:
UniProtKB ID:
基因ID:
  • Human(5571) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(19082) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Rat(25520) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Zebrafish(406440) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • cow(282324) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • dog(486559) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic cat(101094684) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Domestic Rabbit(100356542) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Horse(100034096) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • chicken(429688) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • naked mole-rat(101721085) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic guinea pig(100716757) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • sheep(101103143) protein kinase, AMP-activated, gamma 1 non-catalytic subunit

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Antibodies

货号
说明
物种反应性
应用
Anti-PRKAG1 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human, mouse, rat
应用
ELISA
western blot
Anti-PRKAG1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
物种反应性
human
应用
immunofluorescence
western blot
Anti-PRKAG1 (center) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物种反应性
human, mouse
应用
ELISA
immunohistochemistry

western blot
Anti-PRKAG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
物种反应性
human
应用
immunofluorescence

Proteins

货号
说明
物种
AMPK (α1/β1/γ1),活性,His标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human PRKAG1,
物种
human
MISSION® esiRNA, targeting mouse Prkag1,
物种
mouse