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Merck
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MAPK1

mitogen-activated protein kinase 1

别名:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
物种:
UniProtKB ID:
基因ID:
  • Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(26413) mitogen-activated protein kinase 1
  • Rat(116590) mitogen activated protein kinase 1
  • chicken(373953) mitogen-activated protein kinase 1
  • Zebrafish(360144) mitogen-activated protein kinase 1
  • dog(477575) mitogen-activated protein kinase 1
  • domestic cat(101087614) mitogen-activated protein kinase 1
  • sheep(101115485) mitogen-activated protein kinase 1
  • cow(327672) mitogen-activated protein kinase 1
  • naked mole-rat(101706099) mitogen-activated protein kinase 1
  • domestic guinea pig(100715180) mitogen-activated protein kinase 1

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ELISA

货号
说明
物种
磷酸酪氨酸MAPK1 / MAPK3 ELISA试剂盒, ,
物种
human
检测磷酸化ERK1 / 2 (pThr202 / pTyr204) 的基于细胞的ELISA试剂盒, 96 assays,
物种
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
物种
rat, human, mouse

Antibodies

货号
说明
物种反应性
应用
抗-MAPK 1/2抗体, from rabbit,
物种反应性
bovine, canine, human, mouse, rat
应用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-ERK2 antibody produced in rabbit, ,
物种反应性
human, mouse, rat
应用
immunohistochemistry
western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
物种反应性
human
应用
flow cytometry
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
物种反应性
avian, canine, human, mouse, rat
应用
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-MAPK1 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
物种反应性
human, mouse, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
腺嘌呤, ≥99%,
物种
human, rat, mouse
腺嘌呤, BioReagent, suitable for cell culture,
物种
human, rat, mouse
腺嘌呤, BioReagent, suitable for plant cell culture, ≥99%,
物种
human, rat, mouse

Proteins

货号
说明
物种
ERK2,活性,GST 标记 人, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human MAPK1,
物种
human