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Merck
CN

CASP2

caspase 2, apoptosis-related cysteine peptidase

别名:
CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
物种:
UniProtKB ID:
基因ID:
  • Human(835) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(12366) caspase 2
  • Rat(64314) caspase 2
  • dog(482737) caspase 2, apoptosis-related cysteine peptidase
  • Zebrafish(373118) caspase 2, apoptosis-related cysteine protease
  • chicken(395857) caspase 2, apoptosis-related cysteine peptidase
  • naked mole-rat(101712106) caspase 2, apoptosis-related cysteine peptidase
  • domestic guinea pig(100735399) caspase 2, apoptosis-related cysteine peptidase
  • cow(531419) caspase 2, apoptosis-related cysteine peptidase
  • sheep(101115025) caspase 2, apoptosis-related cysteine peptidase
  • domestic cat(101088318) caspase 2, apoptosis-related cysteine peptidase

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Antibodies

货号
说明
物种反应性
应用
抗胱天冬酶 2抗体,克隆11B4, clone 11B4, Chemicon®, from rat,
物种反应性
canine, human, monkey, mouse
应用
ELISA
flow cytometry

immunoprecipitation (IP)

western blot
Anti-Caspase 2 Antibody, clone 10C6, clone 10C6, Chemicon®, from rat,
物种反应性
canine, human, monkey, mouse
应用
ELISA
flow cytometry

immunoprecipitation (IP)

western blot
Anti-CASP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
immunohistochemistry
Anti-CASP2 antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
immunohistochemistry

western blot
Anti-CASP2 (p18, Cleaved-Gly170) antibody produced in rabbit, affinity isolated antibody,
物种反应性
human
应用
ELISA
western blot

Small Molecule - Inhibitor

货号
说明
物种
Z-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone, powder, ≥95%,
物种
mouse, rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human CASP2,
物种
human
MISSION® esiRNA, targeting mouse Casp2,
物种
mouse