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HomeMILLIPLEX® Multiplex for Luminex® ImmunoassaysMultiplexing Cancer and Metastasis Signaling Pathways

Multiplexing Cancer and Metastasis Signaling Pathways

Cancer and metastasis signaling pathways are notorious for being complex. Read on to see how multiplexing with highly verified MILLIPLEX® multiplex assays can help simplify cancer research by measuring multiple circulating biomarkers at once.

Section Overview


Cancer and Metastasis Signaling Pathways

Cancer and metastasis signaling involves many different pathways including cell signaling, DNA damage, and inflammation. To investigate them, researchers need to analyze various proteins in these pathways such as the Src family kinase, JAK-STAT proteins, TGFβ, NFκB, mTOR, and more. Figure 1 gives a general overview of these pathways and related proteins.

General overview of cancer and metastasis signaling pathways which can be easily analyzed through multiplexing with MILLIPLEX® multiplex immunoassays.

Figure 1Overview of cancer and metastasis signaling pathways highlighting related protein biomarkers.

Download a wall chart PDF of this pathway here .

Multiplexing Signaling Proteins with MILLIPLEX® Multiplex Assays

Multiplexing signaling proteins allows you to measure multiple circulating biomarkers, phosphorylated, or total proteins in a pathway with a single small sample, using intracellular and circulating multiplex assay panels. MILLIPLEX® multiplex assays give you a head start on your research by enabling you to work faster and smarter than traditional techniques, including ELISAs, Western blotting, and flow cytometry. Research areas covered by these panels include:

 

Related Multiplex Panels

View MILLIPLEX® multiplex panels that can be used to analyze specific cancer and metastasis signaling pathways below.

Receptor Tyrosine Kinase (RTK) Signaling
Product No.Product NameDescriptionPricing
HPRTKMAG-01KMILLIPLEX® RTK Phosphoprotein Magnetic Bead Panel- Cell Signaling Multiplex Assayallows simultaneous relative quantitation of multiple proteins in tissue and cell lysate samples
HSCRMAG-32KMILLIPLEX® Human Soluble Cytokine Receptor Panel- Immunology Multiplex AssaySimultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in human serum, plasma and cell culture samples.
HANG2MAG-12KMILLIPLEX® Human Angiogenesis Panel 2, HANG2MAG-12KAngiogenesis Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.

 

 

Src Family Kinase Signaling
Product No.Product NameDescriptionPricing
48-650MAGMILLIPLEX® 8-Plex Human Src Family Kinase Kit – Phosphoprotein - Cancer Multiplex Assay

 

 

Transforming Growth Factor Beta (TGFβ) Signaling
Product No.Product NameDescriptionPricing
48-614MAGMILLIPLEX® TGFβ Signaling Pathway Magnetic Bead 6-Plex - Cell Signaling Multiplex Assay
TGFBMAG-64K-01MILLIPLEX® TGFß1 Magnetic Bead Single Plex Kit - Immunology Multiplex AssayThis Immunology Multiplex Assay is used for the simultaneous quantification of the TGF-β1 biomarker in the following species: Mouse/Human/Rat/Pig/Horse/Rabbit/Guinea Pig/Hamster.
HCCBP1MAG-58KMILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex AssayCirculating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

 

 

Janus Kinase-Signal Transducer and Activator of Transcription (JAK-STAT) Signaling
Product No.Product NameDescriptionPricing
48-610MAGMILLIPLEX MAP STAT Cell Signaling Magnetic Bead 5-Plex Kit - Cell Signaling Multiplex Assay
HAGP1MAG-12KMILLIPLEX® Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex AssayAngiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.
HCCBP1MAG-58KMILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex AssayCirculating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.

 

 

Mitogen-Activated Protein Kinase (MAPK) and Stress-Activated Protein Kinase (SAPK) Signaling
Product No.Product NameDescriptionPricing
48-660MAGMILLIPLEX MAPK/SAPK Signaling 10-Plex Kit - Cell Signaling Multiplex Assay
48-680MAGMILLIPLEX MAP Multi-Pathway Magnetic Bead 9-Plex - Cell Signaling Multiplex Assay
48-681MAGMILLIPLEX® Multi-Pathway Total Magnetic Bead 9-Plex - Cell Signaling Multiplex Assay
HCYTA-60KMILLIPLEX® Human Cytokine/Chemokine/Growth Factor Panel A - Immunology Multiplex Assay
HAGP1MAG-12KMILLIPLEX® Human Angiogenesis/Growth Factor Magnetic Bead Panel - Cancer Multiplex AssayAngiogenesie Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple angiogenic biomarkers in human serum, plasma and cell culture samples.
HCCBP1MAG-58KMILLIPLEX® Human Circulating Cancer Biomarker Magnetic Bead Panel - Cancer Multiplex AssayCirculating Cancer Biomarker Bead-Based Multiplex Assays using the Luminex technology enables the simultaneous analysis of multiple oncology biomarkers in various tumor types in human serum, plasma and cell culture samples.
48-684MAGMILLIPLEX® Ras-Raf Oncoprotein Magnetic Bead Panel 6-Plex - Cell Signaling Multiplex Assay

 

 

 

 

Protein Translation Signaling
Product No.Product NameDescriptionPricing
48-655MAGMILLIPLEX® Protein Translation Magnetic Bead 6-Plex Kit - Cell Signaling Multiplex Assay

 

 

 

 

 

 

 

 

DNA Damage/Genotoxicity Signaling
Product No.Product NameDescriptionPricing
48-621MAGMILLIPLEX® DNA Damage/Genotoxicity Magnetic Bead Panel - Cell Signaling Multiplex Assay

For Research Use Only. Not For Use In Diagnostic Procedures.

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