- Non-covalently solid-phase bound catalysts for organic synthesis.
Non-covalently solid-phase bound catalysts for organic synthesis.
Catalysts immobilized on solid supports have become valuable tools for simplified product isolation and catalyst recycling. An alternative to covalent attachment to a solid support is to immobilize catalysts by non-covalent bonding through hydrogen bridges, or ionic, hydrophobic or fluorous interactions. Compared to covalent attachment, such non-covalent approaches increase the flexibility in the choice of the support material, reaction conditions and work-up strategies. Numerous catalytic reactions employing one of these non-covalent bonding strategies have meanwhile appeared in the literature.