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Merck
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Blazar® Rapid Virus Detection

Our proprietary Blazar® platform is an advanced multiplex and degenerate PCR technology for adventitious and species-specific virus detection that is in line with current regulatory guidance. The Blazar® platform is a targeted molecular method that provides accurate and highly sensitive viral detection in days. By amplifying multiple targets within a conserved region of the viral family genome, our clients can detect a broader range of viruses compared to traditional PCR methods.

  •  FAST - Screen for viruses within days, and release batches sooner incorporating lab automation and digital reporting
  •  SENSITIVE - detect viruses, and any variants, down to as little as 10 genomic copies
  •  SAFE - fully validated and GMP compliant procedure

Related Product Literature


Applications of the Blazar® platform

A multiplex approach that goes beyond single target virus detection

A method for detecting multiple virus families using a single primer set. The image shows three virus families (Virus Family 1 in purple, Virus Family 2 in pink, and Virus Family 3 in grey), each with multiple variants. A single primer set targets multiple sequences from these virus families, shown by arrows pointing to a graph below. The graph displays relative fluorescence units (RFU) against base pairs (bp), with three distinct peaks (Bin1 in purple, Bin2 in pink, and Bin3 in grey) indicating the detection of each virus family. Divided into two sections labeled A and B, represented by green pentagons.

A: Degenerate primers broaden specificity
B: Nested PCR approach enhances sensitivity
C: Fragment detection by capillary electrophoresis. Internal positive controls spiked into each test sample

The Blazar® platform will enable next generation bioprocessing strategies – from process intensification, to connected processing, to fully continuous manufacturing – expediting biomanufacturing timelines thorough enhanced productivity.

Maintain a competitive advantage by accelerating your biologics program with the Blazar® platform for rapid virus detection.


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