502-05A
Human Bronchial Epithelial Cells: HBEpC, adult
Synonym(s):
HBEpC, HBEpC cells
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About This Item
UNSPSC Code:
41106514
NACRES:
NA.81
biological source
human bronchi (normal surface epithelium)
Quality Level
packaging
pkg of 500,000 cells
manufacturer/tradename
Cell Applications, Inc
growth mode
Adherent
karyotype
2n = 46
morphology
epithelial
technique(s)
cell culture | mammalian: suitable
relevant disease(s)
asthma; autoimmune diseases; cardiovascular diseases
shipped in
dry ice
storage temp.
−196°C
General description
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HBEpC provide an excellent model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, inflammation, pulmonary diseases and smoking.
When grown on inserts and provided with the liquid/air interface, HBEpC can differentiate into a pseudostriated epithelium and serve as a more physiological 3D tissue model for in vitro studies.
HBEpC provide an excellent model system to study all aspects of epithelial function and disease, particularly those related to airway viral infections, as well as tissue repair mechanisms, signaling changes and potential treatments relevant to lung injuries, mechanical and oxidative stress, inflammation, pulmonary diseases and smoking.
When grown on inserts and provided with the liquid/air interface, HBEpC can differentiate into a pseudostriated epithelium and serve as a more physiological 3D tissue model for in vitro studies.
Application
epithelial function, tissue repair, cell signaling, lung injury treatment, mechanical and oxidative stress tests, cell differentiation, 3D tissue model, cytokine and growth factor production, apoptosis, cell adhesion molecules, cell permeability, pro-inflammatory signaling, viral fusion mechanisms, gene expression, library screening, mucin secretion
Biochem/physiol Actions
Bronchi
Preparation Note
- 1st passage, >500,000 cells in Cell Basal Medium containing 10% FBS & 10% DMSO
- Can be cultured at least 16 doublings
Please refer to the HBEpC Culture Protocol.
Other Notes
Cell Basal Medium containing 10% FBS & 10% DMSO
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
高风险级别生物产品--人源产品
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Protocols
Technical information for working with human bronchial epithelial cell line including thawing, subculturing and cryopreservation.
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